RESEARCH PAPER
Level of vitamin 25 (OH) D and B group vitamins and functional efficiency among the chronically ill elderly in domiciliary care – a pilot study
 
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1
Department of Family Medicine and Community Nursing, Medical University, Lublin, Poland
 
2
Department of Family Medicine, Medical University, Lublin, Poland
 
3
Institute of Rural Health, Lublin, Poland
 
4
Department of Experimental and Clinical Pharmacology, Medical University, Lublin, Poland
 
 
Corresponding author
Katarzyna Halina Kocka   

Department of Family Medicine and Community Nursing, Medical University of Lublin
 
 
Ann Agric Environ Med. 2019;26(3):489-495
 
KEYWORDS
TOPICS
ABSTRACT
Introduction and objective:
Deficits of vitamin resources constitute a significant public health problem, especially among the elderly population. The aim of the research was to determine the level of vitamin 25 (OH) D and vitamins from group B in the chronically ill elderly in domiciliary care, depending on functional capacity and coexisting diseases.

Material and methods:
The pilot study included 137 patients staying in long-term domiciliary care. Samples of the participants’ venous blood was obtained for laboratory tests. Centrifuged serum was used to determine the level of the following biochemical parameters: vitamin 25 (OH)D, B12, folic acid and total protein, albumin, triglycerides, total cholesterol and HDL cholesterol. Assessment of the functional status of patients was made by using the Barthel scale.

Results:
More than ¾ of the patients with functional deficit (according to Barthel’s score 0–85 points) were deficient in vitamin 25 (OH)D, while folic acid values were below the reference values in more than half of the patients. Respondents with lower functional efficiency were characterised by a reduced average value of vitamin 25 (OH)D and folic acid.

Conclusions:
The studied group of the chronically ill elderly was characterised by a deficiency of vitamin D3 and folic acid. Subjects with a functional impairment deficit show a reduced mean value of vitamin 25 (OH)D and folic acid in the blood serum, compared to the group of patients with higher mobility.

 
REFERENCES (36)
1.
Duda G, Saran A. Polish recommendations concerning vitamins and minerals consumed by elderly people. Farmacja Współczesna. 2008; 1:16–23. (in Polish).
 
2.
Matysiak-Luśnia K. Vitamin D in critically ill patients. AnestIntens Ter. 2016; 48(3): 209–216 (in Polish).
 
3.
Souberbielle JC, Body JJ, Lappe JM, Plebani M, Shoenfeld Y, Wang TJ, et al. Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: recommendations for clinical practice. Autoimmun Rev. 2010; 9(11): 709–715.
 
4.
Płudowski P, Kraśkiewicz E, Karczmarewicz E. Vitamin D provision and supplementation standards. Post Nauk Med. 2012; 25(3): 265–272. (in Polish).
 
5.
Szymański FM, Bomba-Opoń DA, Łęgosz P, Głogowska-Szeląg J, Baran W, Szepietowski JC, et al. Place of vitamin D in everyday clinical practice – an interdisciplinary expert opinion Forum Med Rodz. 2015; 9(6): 423–434. (in Polish).
 
6.
Wojszel ZB. Malnutrition and nutritional therapy dilemmas in geriatrics. Post Nauk Med. 2011; 24(8): 649–657. (in Polish).
 
7.
Lachner C, Steinle NI, Regenold WT. The neuropsychiatry of vitamin B12 deficiency in elderly patients. J Neuropsychiatry Clin Neurosci. 2012; 24(1): 5–15.
 
8.
Andres E, Vogel T, Kaltenbach G, Lang PO. Food-cobalamin malabsorption and vitamin B12 deficiencyin adults and in elderly patiens: What is the problem? Rev Med Interne. 2016; 37(8): 511–513.
 
9.
Andrès E, Vogel T, Federici L, Zimmer J, Ciobanu E, Kaltenbach G. Cobalamin deficiency in elderly patients: a personal view. Curr Gerontol Geriatr Res. 2008; 848267.
 
10.
Cieślik E, Kościej A. Folic acid – occurrence and significances. Probl Hig Epidemiol. 2012; 93(1): 1–7. (in Polish).
 
11.
Zboch M, Gwizdak-Siwkowska B, Serafin J, Śmigórski K, Tyfel P, Leszek J. Deficit of vitamin B12 as a factor affecting development of the dementive process. Med Rodz. 2010; 1:14–19. (in Polish).
 
12.
Luchsinger JA, Tang MX, Miller J, Green R, Mayeux R. Relation of higher folate intake to lower risk of Alzheimer disease in the elderly. Arch Neurol. 2007; 64(1): 86–92.
 
13.
Conzade R, Koenig W, Heier M, Schneider A, Grill E, Peters A, Thorand B. Prevalence and predictors of subclinical micronutrient deficiency in german older adults: results from the population-based KORA-Age study. Nutrients 2017; 9: 1276.
 
14.
Wizner B, Skalska A, Klich-Rączka A, Piotrowicz K, Grodzicki P. Ocena stanu funkcjonalnego u osób w starszym wieku. W: Mossakowska M, Więcek A, Błędowski P. Aspekty medyczne, psychologiczne, socjologiczne i ekonomiczne starzenia się ludzi w Polsce. Poznań: Termedia Wydawnictwa Medyczne; 2012: 81–94 (in Polish).
 
15.
Mahoney FI, Barthel DW. Functional evaluation: the Barthel Index. Md State Med J. 1965; 14: 61–65.
 
16.
Kuźmicz I, Brzostek T, Górkiewicz M. Barthel questionnaire as measurement tool for physical independence of older adults. Stud Med. 2008; 12: 17–21. (in Polish).
 
17.
De Chicco RS, Matarase LE, Seidner D, Steiger E. Biochemical assessment and monitoring of nutritional status. In: R. Latifi, J.S. Dudrick (ed.): The biology and practice of current nutritional support. Landes Bioscience, Georgetown, Teksas 2003.
 
18.
Napiórkowska L, Butlewski T, Jakubas Kwiatkowska W, Hamzy V, Gozdowski D, Franek E. Prevalence of low serum vitamin D concentration in an urban population of elderly women in Poland. Pol Arch Med Wewn. 2009; 119(11): 699–703.
 
19.
Cashman KD, Dowling KG, Škrabáková Z, Gonzalez-Gross M, Valtueña J, Henauw S, et al. Vitamin D deficiency In Europe:pandemic? Am J Clin Nutr. 2016; 103(4): 1033–1044.
 
20.
Lips P, Duong T, Oleksik A, Black D, Cummings S, Cox D, et al. A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial. J Clin Endocrinol Metab. 2001; 86(3): 1212–1221.
 
21.
Hoogendijk JG, Lips P, Dik MG, Deeg DJ, Beekman AT, Penninx BW. Depression is associated with decreased 25-hydroxyvitamin D and increased parathyroid hormone levels in older adults. Arch Gen Psychiatr. 2008; 65(5): 508–512.
 
22.
Passeri M, Pini G, Troiano L, Vescovini R, Sansoni P, Passeri M, et al. Low vitamin D status, high bone turnover, and bone fractures in centenarians. J Clin Endocrinol Med. 2003; 88(11): 5109–5115.
 
23.
Jurkowlaniec E. Disorders of biological rhythms resulting from light pollution – selected physiological aspects of melatonin and vitamin d deficiency. Pol J Environ Stud. 2017; 21(2): 47–57. (in Polish).
 
24.
Zabrocka J, Wojszel ZB. Vitamin B12 deficiency in old age – causes, consequences and therapeutic approach. Geriatria. 2013; 7: 24–32. (in Polish).
 
25.
Suter PM. Vitamin Nutriture in Older Adults. In: Chernoff R. (ed.). Geriatric nutrition. The health professional’s handbook. 4rd ed. Jones and Bartlett Publishers; 2014: 35–79.
 
26.
Cuskelly GJ, Money KM, Young IS. Folate and vitamin B12: friendly or enemy nutrients for the elderly. Proc Nutr Soc. 2007; 66(4): 548–558.
 
27.
Loikas S, Koskinen P, Irjala K, Löppönen M, Isoaho R, Kivelä SL, et al. Vitamin B12 deficiency in the aged: a population-based study. Age Ageing. 2007; 36(2): 177–183.
 
28.
Wierzbicka E, Brzozowska A, Roszkowski W. Energy and nutrient intake of elderly people living in the Warsaw region, Poland. J Nutr Health Aging. 2001; 5(4): 248–252.
 
29.
Noronha BM, Cunha AN, Araújo AD, Abrunhosa FS, Rocha NA, Amaral FT. Undernutrition, serum vitamin B12, folic acid and depressive symptoms in older adults. Nutr Hosp. 2015; 32(1): 354–361.
 
30.
Van Pottelberg G, Mathei C, Vaes B, Adriaensen W, Gruson D, Degryse JM. The influence of renal function on vitamin D metabolism in the very elderly. J Nutr Health Aging. 2013; 17(2): 107–111.
 
31.
Rafiq R, Prins HJ, Boersma WG, Daniels JM, den Heijer M, Lips P, et al. Effects of daily vitamin D supplementation on respiratory muscle strength and physical performance in vitamin D-deficient COPDpatients: a pilot trial. Int J Chron Obstruct Pulmon Dis. 2017; 28 (12): 2583–2592.
 
32.
Walkiewicz KW, Dzięgielewska-Gęsia S, Fatyga E, Giętek M, Kozieł P,Muc-Wierzgoń M, et al. Cognitive impairment in elderly patients considering concentration of hemoglobin and vitamin B 12 – preliminary report. Fam Med Primary Care Rev. 2015; 3: 225–228. (in Polish).
 
33.
Bronkowska M, Karcz I. Assessment of vitamins contents in the food rations of low physically active women. Rocz Panstw Zakl Hig. 2007; 58(3): 533–540. (in Polish).
 
34.
Kennedy DO. B Vitamins and the brain: mechanisms, dose and efficacy- a review. Nutrients. 2016; 8(2): 68.
 
35.
Czeczot H. Folic acid in physiology and pathology. Postepy Hig Med Dosw. 2008; 62: 405–419. (in Polish).
 
36.
Caccamo D, Ricca S, Currò M, Ientile R. Health risks of hypovitaminosis D: a review of new molecular insights. Int J Mol Sci. 2018; 19(3): E892.
 
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ISSN:1232-1966
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