Seroprevalence of leptospirosis in rural populations inhabiting areas exposed and not exposed to floods in eastern Poland
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Department of Swine Diseases, National Veterinary Research Institute, Puławy, Poland
Department of Parasitology, National Veterinary Research Institute, Puławy, Poland
Department of Zoonoses, Institute of Rural Health, Lublin, Poland
Department of Epidemiology, Warsaw Medical University, Warsaw, Poland
Corresponding author
Jacek Dutkiewicz   

Department of Zoonoses, Institute of Rural Health, Lublin, Poland
Ann Agric Environ Med. 2012;19(2):285-288
Blood serum samples collected from randomly selected groups of 100 persons inhabiting rural community ‘A’ located in eastern Poland and exposed to floods by the Vistula river, and 98 persons inhabiting rural community ‘B’, also located in eastern Poland, but in the area not exposed to floods were examined by the microscopic agglutination test (MAT) for the presence of antibodies against 18 Leptospira serovars. Positive results showed 3% of serum samples collected from community ‘A’, while the seroprevalence in community ‘B’ was 9.2%, being insignificantly higher than in community ‘A’. For both examined communities (n=198), a significant positive correlation was found between the prevalence and titer of seropositive response and age of examined people (r=0.145, p=0.042). No significant differences were found between the prevalence of positive reactions in males and females (p>0.05). The reactions with 10 serovars of Leptospira (Australis, Autumnalis, Hebdomadis, Hardjo, Sejroe, Zanoni, Bataviae, Bratislava, Canicola and Grippotyphosa), belonging to 3 species (L. interrogans, L. borgpetersenii, L. kirschneri), were found in the examined communities. From both communities, of 12 persons demonstrating positive results in MAT, 9 showed reaction with one serovar, 2 with two serovars and 1 with three serovars. The highest titers found during the examination did not exceeded 800. In conclusion, our results suggest that there is only a slight, if any, hazard of an leptospirosis epidemic after the flood that afflicted eastern Poland in the year 2010 and the general epidemiological situation of leptospirosis in eastern Poland. Although there does not seem to be any cause for concern, further research is needed.
Adler B, de la Peña Moctezuma A. Leptospira and leptospirosis. Vet Microbiol. 2010; 140: 287-296.
Adler B, de la Peña Moctezuma A. Leptospira. In: Gyles CL, Prescot JF, Songer JG, Thoen CO. Pathogenesis of bacterial infections in animals. 4th ed. Willey-Blackwell, 2010. p. 572-547.
Monahan A, Miller I, Nally J. Leptospirosis risk during recreational activities. J Appl Microbiol. 2009; 107: 707-716.
Faine S. Leptospira and leptospirosis. 1st ed. CRC Press, Boca Raton; 1994.
Dutkiewicz J, Cisak E, Sroka J, Wójcik-Fatla A, Zając V. Biological agents as occupational hazards – selected issues. Ann Agric Environ Med. 2011; 18: 286-293.
Vijayachari P, Sugunan AP, Shriram AN. Leptospirosis: an emerging global public health problem. J Biosci. 2008; 33: 557-69.
Cruz 2009 Cruz LS, Vargas R, Lopes AA. Leptospirosis: a worldwide resurgent zoonosis and important cause of acute renal failure and death in developing nations. Ethn Dis. 2009; 19(Suppl 1): S1-37-41.
Evangelista KV, Coburn J. Leptospira as an emerging pathogen: a review of its biology, pathogenesis and host immune responses. Future Microbiol. 2010; 5: 1413-1425.
Pappas G, Papadimitriou P, Siozopoulou V, Christou L, Akritidis N. The globalization of leptospirosis: worldwide incidence trends. Int J Infect Dis. 2008; 12: 351-357.
Hartskeerl RA, Collares-Pereira M, Ellis WA. Emergence, control and re-emerging leptospirosis: dynamics of infection in the changing world. Clin Microbiol Infect. 2011; 17: 494-501.
Dutkiewicz J, Śpiewak R, Jabłoński L, Szymańska J. Biological Agents of Occupational Risk. Classification, Exposed Professional Populations, Measurements, Prevention. Ad Punctum, Lublin; 2007 (in Polish).
Lau CL, Smythe LD, Craig SB, Weinstein P. Climate change, flooding, urbanisation and leptospirosis: fuelling the fire? Trans R Soc Trop Med Hyg. 2010; 104: 631-638.
Zwierz J. Marsh fever in Silesia. Pol Tyg Lek. 1951; 6: 1510-1515 (in Polish).
Zwierz J. Leptospiroses. Edition 2. PZWL, Warsaw 1964 (in Polish).
Schoonman L, Swai ES. Risk factors associated with the seroprevalence of leptospirosis, amongst at-risk groups in and around Tanga city, Tanzania. Ann Trop Med Parasitol. 2009; 103: 711-718.
Onyemelukwe NF. A serological survey for leptospirosis in the Enugu area of eastern Nigeria among people at occupational risk. J Trop Med Hyg. 1993; 96: 301-304.
Cacciapuoti B, Nuti M, Pinto A, Sabrie AM. Human leptospirosis in Somalia: a serological survey. Trans R Soc Trop Med Hyg. 1982; 76: 178-182.
Sharma S, Vijayachari P, Sugunan AP, Natarajaseenivasan K, Sehgal SC. Seroprevalence of leptospirosis among high-risk population of Andaman Islands, India. Am J Trop Med Hyg. 2006; 74: 278-283.
Elbers AR, Vecht U, Osterhaus AD, Groen J, Wisselink HJ, Diepersloot RJ, Tielen MJ. Low prevalence of antibodies against the zoonotic agents Brucella abortus, Leptospira spp., Streptococcus suis serotype II, hantavirus, and lymphocytic choriomeningitis virus among veterinarians and pig farmers in the southern part of The Netherlands. Vet Q 1999; 21: 50-54.
Bokhout BA, Peterse DJ, Koger PL, Terpstra WJ. The occurrence of hardjo-positive dairy cows in the Northern Netherlands. A prospective serological survey. Tijdschr Diergeneeskd 1989; 114: 123-130 (in Dutch).
Campagnolo ER, Warwick MC, Marx HL Jr, Cowart RP, Donnell HD Jr, Bajani MD, Bragg SL, Esteban JE, Alt DP, Tappero JW, Bolin CA, Ashford DA. Analysis of the 1998 outbreak of leptospirosis in Missouri in humans exposed to infected swine. J Am Vet Med Assoc. 2000; 216: 676-682.
Stanford CF, Connolly JH, Ellis WA, Smyth ET, Coyle PV, Montgomery WI, Simpson DI. Zoonotic infections in Northern Ireland farmers. Epidemiol Infect. 1990; 105: 565-570.
Nuti M, Amaddeo D, Crovatto M, Ghionni A, Polato D, Lillini E, Pitzus E, Santini GF. Infections in an Alpine environment: antibodies to hantaviruses, leptospira, rickettsiae, and Borrelia burgdorferi in defined Italian populations. Am J Trop Med Hyg. 1993 ;48: 20-25.
Fenga C, Spatari G, Cacciola A, Ioli A. Serologic investigation on the prevalence of Leptospira spp. infection in occupationally exposed subjects. Med Lav. 2004; 95: 441-446 (in Italian).
Bolin CA. Leptospirosis. In: OIE Manual of Standards for Diagnostic Tests and Vaccines for Terrestrial Animals. Office International des Epizooties 2008, pp. 251-264.
Wasiński B, Pejsak Z. Occurrence of leptospiral infections in swine population in Poland evaluated by ELISA and microscopic agglutination test. Pol J Vet Sci. 2010; 13: 695-699.
Korczyńska A, Suchowiak J. An epidemic of marsh fever in the Wroclaw Province in 1971. Przegl Epidemiol. 1973; 27: 563-568 (in Polish).
Hałat Z, Korczyńska A, Kasiński J. Leptospirosis outbreak in the Wrocław Province in 1974. Przegl Epidemiol. 1976; 30: 491-495 (in Polish).
Litarska U, Knap JP, Zieba J. Leptospirosis laboratory of WSSE in Wrocław (1947-2005). Comment on its activity. Przegl Epidemiol. 2006; 60: 213-224 (in Polish).
Parnas J. The organization and methods of investigations on swamp fever in the province if Lublin. A field trial in 1955-1957. Przegl Epidemiol. 1958; 12: 1-4 (in Polish).
Uziak S. The results of soil investigations in foci of swamp fever in rural areas of the Lublin province. Przegl Epidemiol. 1958; 12: 43-49 (in Polish).
Cechowicz W, Hryniewicz H. Zoological and ecological investigations on small mammals in natural foci of leptospirosis in the Lublin province. Przegl Epidemiol. 1958; 12: 25-28 (in Polish).
Parnas J, Dąbrowski T, Łazuga K, Koślak A, Paroszkiewicz M. Microbiological investigations on leptosirosis inn small mammals and in domestic animals in the district of Tomaszów Lubelski. Przegl Epidemiol. 1958; 12: 29-34 (in Polish).
Łazuga K. Microbiological and serological investigations on leptospirosis in the province of Lublin (1956-57). Przegl Epidemiol. 1958; 12: 5-7 (in Polish).
Patorska-Mach E, Mierzejewska I, Kornaś B. Leptospiroses in the Chełm province. Przegl Epidemiol. 1978; 32: 323-329 (in Polish).
Juszczyk J, Lewkowicz H, Adamek J, Furmaniuk J, Klemczak K, Szkaradkiewicz A, Kiczka W. Occurrence of antibodies against Listeria, Bedsonia, Leptospira and Brucella in workers of animal husbandry farms in the Poznań region. Przegl Epidemiol. 1984; 38: 11-18 (in Polish).
Cybulska M, Doleżko-Marciniak H, Hencner Z. Serologic investigations for leptospira infections in humans in the Province of Lublin in the years 1966-1971. Pol Tyg Lek. 1973; 28: 733-735 (in Polish).
Krawczyk M. Estimation of transmission hazard of Leptospira sp. infections in 2 groups of people. Przegl Epidemiol. 2004; 58: 207-212 (in Polish).
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