Metabolic syndrome in Poland – the PONS Study
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Faculty of Medicine, Department of Public Health, University Medical Centre, Norwegian University of Science and Technology, Trondheim, Norway
Department of Cancer Epidemiology and Prevention, the Maria Skłodowska-Curie Cancer Centre and Institute of Oncology, Warsaw, Poland
Ann Agric Environ Med. 2011;18(2):270-272
In Central and Eastern European countries, cardiovascular disorders (CVD) in middle age are much more common than in Western Europe, and it is imperative to understand the causes underlying this excess disease burden. The metabolic syndrome comprises a constellation of metabolic abnormalities that increase the risk of cardiovascular disease.

Material and Methods:
Data were obtained by structured interview, and by measurements of anthropometric factors and blood analyses among 3,862 individuals. Metabolic syndrome was defined according the International Diabetes Federation Task Force on Epidemiology and Prevention, as the presence of at least 3 of 5 abnormalities: 1) abdominal obesity, 2) glucose intolerance, 3) high triglycerides, 4) low HDL cholesterol, 5) high blood pressure.

Overall, 1,518 participants (39.5%) had metabolic syndrome. The prevalence among females was 34.3% (877 females) vs. 49.9% (641 males) among males, and increased with age in both genders. Abdominal obesity was the most common abnormality (2,897 participants, 75.1%), followed by high blood pressure (2,741 participants, 71%), glucose intolerance (1,437 participants, 37.3%), elevated triglycerides (817 participants, 21.2%) and low HDL (615 participants, 15.9%).

The prevalence of metabolic syndrome and metabolic abnormalities is high and represents strong risk factors for CVD morbidity and mortality. However, these factors are all potentially preventable by lifestyle modification and/or by pharmacological treatment. There is an urgent need for the health service to act, and to increase public awareness of metabolic syndrome.

Bobak M, Marmot M. East-West mortality divide and its potential explanations: proposed research agenda. Bmj 1996;312(7028):421-5.
Chen K, Lindsey JB, Khera A, De Lemos JA, Ayers CR, Goyal A, et al. Independent associations between metabolic syndrome, diabetes mellitus and atherosclerosis: observations from the Dallas Heart Study. Diab Vasc Dis Res 2008;5(2):96-101.
Despres JP, Lamarche B, Mauriege P, Cantin B, Dagenais GR, Moorjani S, et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med 1996;334(15):952-7.
Despres JP, Marette A. Relation of components of insulin resistance syndrome to coronary disease risk. Curr Opin Lipidol 1994;5(4):274-89.
Isomaa B, Almgren P, Tuomi T, Forsen B, Lahti K, Nissen M, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 2001;24(4):683-9.
Mensah GA, Mokdad AH, Ford E, Narayan KM, Giles WH, Vinicor F, et al. Obesity, metabolic syndrome, and type 2 diabetes: emerging epidemics and their cardiovascular implications. Cardiol Clin 2004;22(4):485-504.
Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009;120(16):1640-5.
Galassi A, Reynolds K, He J. Metabolic syndrome and risk of cardiovascular disease: a meta-analysis. Am J Med 2006;119(10):812-9.
Riediger ND, Clara I. Prevalence of metabolic syndrome in the Canadian adult population. CMAJ 2011;183(15):E1127-34.
Ford ES, Giles WH, Mokdad AH. Increasing prevalence of the metabolic syndrome among u.s. Adults. Diabetes Care 2004;27(10):2444-9.
Cameron AJ, Shaw JE, Zimmet PZ. Th e metabolic syndrome: prevalence in worldwide populations. Endocrinol Metab Clin North Am 2004;33(2):351-75, table of contents.
Wyrzykowski B, Zdrojewski T, Sygnowska E, Biela U, Drygas W, Tykarski A, et al. Epidemiologia zespołu metabolicznego w Polsce. Wyniki programu WOBASZ. (Epidemiology of metabolic syndrome in Poland. Results of the WOBASZ program). Kardiol Pol 2005;63(6 Suppl 4):S641-4 (in Polish).
Skrabski A, Kopp M, Kawachi I. Social capital in a changing society: cross sectional associations with middle aged female and male mortality rates. J Epidemiol Community Health 2003;57(2):114-9.
Kopp MS, Skrabski A, Laszlo KD, Janszky I. Gender patterns of socioeconomic diff erences in premature mortality: follow-up of the Hungarian Epidemiological Panel. Int J Behav Med 2011;18(1):22-34.
Dennis BH, Zhukovsky GS, Shestov DB, Davis CE, Deev AD, Kim H, et al. Th e association of education with coronary heart disease mortality in the USSR Lipid Research Clinics Study. Int J Epidemiol 1993;22(3):420-7.
Mackenbach JP, Stirbu I, Roskam AJ, Schaap MM, Menvielle G, Leinsalu M, et al. Socioeconomic inequalities in health in 22 European countries. N Engl J Med 2008;358(23):2468-81.
Poręba R, Skoczyńska A, Gać P, Poręba M, Jędrychowska I, Aff elskaJercha A, Turczyn B, Wojakowska A, Oszmiański J, Andrzejak R. Drinking of chokeberry juice from the ecological farm Dzięciołowo and distensibility of brachial artery in men with mild hypercholesterolemia. Ann Agric Environ Med 2009;16:305–308.
Puska P. From Framingham to North Karelia: from descriptive epidemiology to public health action. Prog Cardiovasc Dis 2010;53(1):15-20.
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