CASE REPORT
Acute respiratory distress syndrome (ARDS) in the course of influenza A/H1N1v infection – genetic aspects
1
Military Institute of Hygiene and Epidemiology, Biological Threat Identification and Countermeasures Centre, Pulawy, Poland
2
BioVectis, Warsaw, Poland; Electron Microscopy Platform, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
3
Department of Expert Medical Assistance with Emergency Medicine Unit, Medical University, Lublin, Poland
4
BioVectis, Warsaw, Poland
5
Department of Internal Medicine, Independent Public Clinical Hospital, Lublin, Poland
Corresponding author
Katarzyna Naylor
Department of Expert Medical Assistance with Emergency Medicine Unit, Medical University, Lublin, Poland
Department of Expert Medical Assistance with Emergency Medicine Unit, Medical University, Lublin, Poland
Ann Agric Environ Med. 2013;20(4):711–714
KEYWORDS
ABSTRACT
Influenza is a contagious respiratory disease caused by viruses belonging to the family Ortomyxoviridae. Among the influenza viruses type A, B and C, the A type virus shows the most pathogenic potential. Its surface receptor glycoproteins, hemagglutinin (HA) and neuraminidase (NA), are characterized by high antigenic variation, thus a host organism cannot develop permanent resistance. The case is described of a male patient with severe acute respiratory distress syndrome in the course of influenza A/N1H1v infection, confirmed by virological molecular analysis. During diagnostic procedures based on the MSSCP genotyping it was observed that the WHO recommended RT-PCR kits and/or procedure of sample collection from patients for molecular investigation could lead to false positive A/H1N1 pandemic strain detection because of the co-amplification during the RT-PCR fragments of the human genome.
REFERENCES (20)
1.
Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med. 2009; 360: 2605–15. [Erratum: N Engl J Med. 2009; 361: 102].
2.
De la Rosa-Zamboni D, Vázquez-Pérez JA, Avila-Ríos S, Carranco-Arenas AP, Ormsby CE, Cummings CA, Soto-Nava M, Hernández-Hernández VA, Orozco-Sánchez CO, la Barrera CA, Pérez-Padilla R, Reyes-Terán G. Molecular. Characterization of the Predominant Influenza A(H1N1)pdm09 Virus in Mexico, December 2011-February 2012. PLoS One 2012; 7(11): e50116.
3.
Morales-García G, Falfán-Valencia R, García-Ramírez RA, Camarena A, Ramirez-Venegas A, Castillejos-López M, Pérez-Rodríguez M, González-Bonilla C, Grajales-Muñíz C, Borja-Aburto V, Mejía-Aranguré JM. Pandemic influenza A/H1N1 virus infection and TNF, LTA, IL1B, IL6, IL8, and CCL polymorphisms in Mexican population: a case-control study. BMC Infect Dis. 2012; 12(1): 299.
4.
Borja-Aburto VH, Chowell G, Viboud C, Simonsen L, Miller MA, Grajales-Muñiz C, González-Bonilla CR, Diaz-Quiñonez JA, Echevarría-Zuno S. Epidemiological Characterization of a Fourth Wave of Pandemic A/H1N1 Influenza in Mexico, Winter 2011–2012: Age Shift and Severity. Arch Med Res. 2012; 43(7): 563–70.
5.
Chowell G, Echevarría-Zuno S, Viboud C, Simonsen L, Grajales Muñiz C, Rascón Pacheco RA, González León M, Borja Aburto VH. Recrudescent wave of pandemic A/H1N1 influenza in Mexico, winter 2011–2012: Age shift and severity. PLoS currents 2012; 4: RRN1306.
6.
Jaber S, Conseil M, Coisel Y, Jung B, Chanques G. ARDS and influenza A (H1N1): patients’ characteristics and management in intensive care unit. Ann Fr Anesth Reanim. 2010; 29(2): 117–25.
7.
Homsi S, Milojkovic N, Homsi Y. Clinical pathological characteristics and management of acute respiratory distress syndrome resulting from influenza A (H1N1) virus. South Med J. 2010; 103(8): 786–90.
8.
Kato Y. Pneumonia and acute respiratory distress syndrome due to pandemic influenza H1N1 2009 Nippon Rinsho. 2010; 68(9): 1666–70.
9.
Chowell G, Viboud C, Simonsen L, Miller MA, Echevarría-Zuno S, González-León M, Aburto VH. Impact of antiviral treatment and hospital admission delay on risk of death associated with 2009 A/H1N1 pandemic influenza in Mexico. BMC Infect Dis. 2012; 12: 97.
10.
Charu V, Chowell G, Palacio Mejia LS, Echevarría-Zuno S, Borja-Aburto VH, Simonsen L, Miller MA, Viboud C. Mortality burden of the A/H1N1 pandemic in Mexico: a comparison of deaths and years of life lost to seasonal influenza. Clinical infectious diseases. Infect Dis Soc Am. 2011; 53(10): 985–93.
11.
Wu W, Kang X, Bai Z, Liu L, Li J, Wu X, Sun H, Hu T, Yang M, Wang P, Liu L, Yang Y, Di B, Chen W. Detection of pandemic influenza A/H1N1/2009 virus by real-time reverse transcription polymerase chain reaction. J Virol Methods 2010; 165(2): 294–6.
12.
Rodríguez-Valero M, Prado Calleros HM, Bravo Escobar GA, Valdez Vázquez RR, Figueroa Moreno R, Martínez Montes G, Kawa Karasik S. Difference between early clinical features of swine origin A H1N1 influenza confirmed and not confirmed infection in Mexico . J Infect Devel Count. 2012; 6(4): 302–10.
13.
Kaczanowski R, Trzeciak L, Kucharczyk K. Multitemperature single-strand conformation polymorphism. Electrophoresis. 2001; 22: 3539–3545.
14.
Sanger F, Nicklen S, Coulson AR. DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci. USA 1997; 74: 5463–5467.
15.
Ducatez MF, Sonnberg S, Hall RJ, Peacey M, Ralston J, Webby RJ, Huang QS. Genotyping assay for the identification of 2009–2010 pandemic and seasonal H1N1 influenza virus reassortants . J Virol Methods 2010; 168(1–2): 78–81.
16.
Pajak B, Stefanska I, Lepek K, Donevski S, Romanowska M, Szeliga M, Brydak LB, Szewczyk B, Kucharczyk K. Rapid differentiation of mixed influenza A/H1N1/infections with seasonal and pandemic variants by multi-temperature single-stranded conformational polymorphism. J Clin Microbiol. 2011; 49(6): 2216–2221.
17.
Nakauchi M, Yasui Y, Miyoshi T, Minagawa H, Tanaka T, Tashiro M, Kageyama T. One-step real-time reverse transcription-PCR assays for detecting and subtyping pandemic influenza A/H1N1 2009, seasonal influenza A/H1N1, and seasonal influenza A/H3N2 viruses. J Virol Methods 2011; 171(1): 156–62.
18.
Hymas WC, Mills A, Ferguson S, Langer J, She RC, Mahoney W, Hillyard DR. Development of a multiplex real-time RT-PCR assay for detection of influenza A, influenza B, RSV and typing of the 2009-H1N1 influenza virus . J Virol Methods 2010; 167(2): 113–8.
19.
Castro-Cárdenas LA, Llaca-Díaz JM, Pérez-Chávez F, Gómez-Espinel IA, Flores-Aréchiga A. Comparative study of a rapid testing with real time RT-PCR for diagnosis of influenza AH1N1 2009. Salud pública de México 2009; 53(4): 329–33.
20.
Cunha BA, Corbett M, Mickail N. Human parainfluenza virus type 3 (HPIV 3) viral community-acquired pneumonia (CAP) mimicking swine influenza (H1N1) during the swine flu pandemic. Heart Lung. 2011; 40(1): 76–80.
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