CASE REPORT
Sepsis caused by Chromobacterium violaceum – probably the first case in Europe, or Macbeth read anew
 
More details
Hide details
1
Departament of Nephrology, Endocrinology, Hypertension and Internal Medicine, Pope John Paul II Regional Hospital in Zamosc, Poland
2
Faculty of Health Sciences University of Economics and Innovation, Lublin, Poland
CORRESPONDING AUTHOR
Krzysztof Marczewski   

Departament of Nephrology, Endocrinology, Hypertension and Internal Medicine, Pope John Paul II Regional Hospital in Zamosc, Poland
 
Ann Agric Environ Med. 2019;26(3):508–510
KEYWORDS
TOPICS
ABSTRACT
Rare diseases, almost by definition, present us with diagnostic as well as therapeutic difficulties as. They also include infectious diseases outside endemic areas. Without expecting them, we are not preparing to fight them. Like Macbeth, we feel safe, convinced that tropical diseases do not reach us, like Birnam forest towards his castle. Nevertheless, the forest moved according to the prophecy of the three witches, and in a similar way tropical flora is moving towards us according to the predictions of environmentalists. This is illustrated by the history of the presented patient, who was admitted to hospital because of sepsis caused by Chromobacterium violaceum (CV), a Gram-negative facultatively anaerobic, oxidase-positive bacterium producing a dark violet antioxidant pigment called violacein. This is probably the first documented case report of sepsis in this part of the world. To the best of the authors’ knowledge, the patient is the first to require dialysis after Chromobacterium violaceum infection.
 
REFERENCES (14)
1.
Darmawan G, Kusumawardhani RNY, Alisjahbana B, Fadjari TH. Chromobacterium violaceum: The Deadly Sepsis. Acta Med Indones. 2018 Jan; 50(1):80–81.
 
2.
Karthik R, Pancharatnam P, Balaji V. Fatal Chromobacterium violaceum septicemia in a South Indian adult. J Infect Dev Ctries. 2012 Oct 19; 6(10): 751–5.
 
3.
Cheong BM. A fatal case of pulmonary chromobacterium violaceum infection in an adult. Med J Malaysia. 2010 Jun; 65(2):148–9.
 
4.
Schattenberg HJ, Harris WH. Chromobacterium violaceum, Var. Manilae as a Pathogenic Microörganism. J Bacteriol. 1942 Nov; 44(5): 509–21.
 
5.
Ravish Kumar M. Chromobacterium violaceum: A rare bacterium isolated from a wound over the scalp. Int J Appl Basic Med Res. 2012 Jan-Jun; 2(1): 70–72.
 
6.
Stojek NM, Dutkiewicz J. Studies on the occurrence of Gram-negative bacteria in ticks: Ixodes ricinus as a potential vector of Pasteurella. Ann Agric Environ Med. 2004; 11(2): 319–22.
 
7.
Cheong BM. A fatal case of pulmonary chromobacterium violaceum infection in an adult. Med J Malaysia. 2010 Jun;5(2):48–9.
 
8.
Lin Yd, Majumdar SS, Hennessy J, Baird RW. The Spectrum of Chromobacterium violaceum Infections from a Single Geographic Location. Am J Trop Med Hyg. 2016 Apr;94(4):710–6.
 
9.
Arosio M, Raglio A, Ruggeri M, Serna Ortega P, Morali L, De Angelis C, Goglio A. Chromobacterium violaceum lymphadenitis successfully treated in a northern Italian hospital. New Microbiol. 2011; 34: 429–432.
 
10.
Hagiya H, Murase T, Suzuki M, Shibayama K, Kokumai Y, Watanabe N, Maki M, Otsuka F. Chromobacterium violaceum nosocomial pneumonia in two Japanese patients at an intensive care unit. J Infect Chemother. 2014 Feb; 20(2): 139–42.
 
11.
http://www.noaanews.noaa.gov/s... (06.04.2018 15:40).
 
12.
Gonçalves PR, Rocha-Brito KJ, Fernandes MR, Abrantes JL, Durán N, Ferreira-Halder CV. Violacein induces death of RAS-mutated metastatic melanoma by impairing autophagy process. Tumour Biol. 2016 Oct; 37(10): 14049–14058.
 
13.
Alshatwi AA, Subash-Babu P, Antonisamy P. Violacein induces apoptosis in human breast cancer cells through up regulation of BAX, p53 and down regulation of MDM2. Exp Toxicol Pathol. 2016 Jan;8(1):9–97.
 
14.
Justo GZ, Durán N. Action and function of Chromobacterium violaceum in health and disease: Violacein as a promising metabolite to counteract gastroenterological diseases. Best Pract Res Clin Gastroenterol. 2017 Dec; 31(6): 649–656.
 
eISSN:1898-2263
ISSN:1232-1966