RESEARCH PAPER
Quality of life in parents of children and adolescents after systemic sting reactions
 
More details
Hide details
1
Department of Paediatrics, Jagiellonian University Medical College, Krakow, Poland
2
DZIUPLA Statistical analysis, Krakow, Poland
 
KEYWORDS:
TOPICS:
ABSTRACT:
Introduction and objectives:
The study aimed at evaluating the impact of Hymenoptera venom allergy (HVA) in children and adolescents, on their parents’ QoL, taking into account their socio-demographic characteristics.

Material and methods:
The study sample consisted of 101 parents of children and adolescents aged 9–17 years, with a history of systemic reaction after insect sting who were referred for consultations in the tertiary level allergology department. The mean age of the parents was 39 years (SD=8.1; range 25–65 years); the majority were mothers (68%) and rural inhabitants (62%). QoL in parents of HVA children and adolescents was measured with the Parents of Children with Hymenoptera Venom Allergy Quality of Life Scale, a questionnaire covering 5 dimensions: anxiety, caution, limitations and discomfort, support provided to the child and feeling of safety, each measured on the scale ranging from 1 to 5. Independent predictors of QoL were estimated using the Generalized Linear Model.

Results:
Parents of urban children and adolescents treated with venom immunotherapy (VIT) up to 3 years (B=-1.37, 95CI= (-2.22;-0.53); p=0.001) and of rural children treated for more than 3 years (B=-0.94, 95CI=(-1.55;-0.33); p=0.003) reported lower anxiety than parents studied at diagnosis. In urban parents, individuals studied at VIT beginning reported a lower feeling of safety (B=-0.63, 95CI=(-1.11;-0.15); p=0.010); those studied up to 3 years of treatment reported a higher feeling of safety (B=0.64, 95CI=(0.11;1.16); p=0.018) than those studied at diagnosis. Contrariwise, in rural parents, those studied at the beginning of immunotherapy reported a higher feeling of safety than those studied at diagnosis (B=0.51, 95CI=(0.13;0.88); p=0.008).

Conclusions:
The longest VIT duration in children and adolescents with HVA is related to the decreased anxiety of their parents. Parent’s feeling of safety depends on the stage of treatment and place of residence.

CORRESPONDING AUTHOR:
Piotr Brzyski   
DZIUPLA Statistical analysis, Jaremy 5/6, 31-318 Kraków, Poland
 
REFERENCES (29):
1. Biló BM, Rueff F, Mosbech H, Bonifazi F, Oude-Elberink JNG, the EAACI Interest Group on Insect Venom Hypersensitivity. Diagnosis of Hymenoptera venom allergy. Allergy 2005; 60: 1339–1349.
2. Grabenhenrich LB, Dölle S, Moneret-Vautrin A, Köhli A, Lange L, Spindler T, et al. Anaphylaxis in children and adolescents: The European Anaphylaxis Registry. J Allergy Clin Immunol. 2016; 137: 1128–1137.e1.
3. Juniper EF, Guyatt GH, Feeny DH, Ferrie PJ, Griffith LE, Townsend M. Measuring quality of life in the parents of children with asthma. Qual Life Res. 1996; 5: 27–34.
4. Silva CM, Barros L, Simões F. Health-related quality of life in paediatric asthma: children’s and parents' perspectives. Psychol Health Med. 2015; 8: 940–954.
5. Cianchetti C, Bianchi E, Guerrini R, Baglietto MG, Briguglio M, Cappelletti S, et al. Symptoms of anxiety and depression and family’s quality of life in children and adolescents with epilepsy. Epilepsy Behav. 2018; 79: 146–153.
6. Gomes MC, Pinto-Sarmento TC de A, Costa EMM de B, Martins CC, Granville-Garcia AF, Paiva SM. Impact of oral health conditions on the quality of life of preschool children and their families: a cross-sectional study. Health Qual Life Outcomes. 2014; 12: 55.
7. Kiliś-Pstrusińska K, Medyńska A, Adamczyk P, Bałasz-Chmielewska I, Grenda R, Kluska-Jóźwiak A, et al. Disease-related social situation in family of children with chronic kidney disease – parents` assessment. A multicentre study. Ann Agric Environ Med. 2014; 21: 876–881.
8. Turan E, Kandemir H, Yeşilova Y, Ekinci S, Tanrikulu O, Kandemir SB, et al. Assessment of psychiatric morbidity and quality of life in children and adolescents with cutaneous leishmaniasis and their parents. Adv Dermatology Allergol. 2015; 5: 344–348.
9. Yoshihara S, Kanno N, Fukuda H, Arisaka O, Arita M, Sekine K, et al. Caregiver treatment satisfaction is improved together with children’s asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms. Allergol Int. 2015; 64: 371–376.
10. Chernyshov P V. Gender differences in health-related and family quality of life in young children with atopic dermatitis. Int J Dermatol. 2012; 51: 290–294.
11. Brzyski P, Cichocka-Jarosz E, Lis G, Tobiasz-Adamczyk B. Development of parents’ of children with Hymenoptera Venom Allergy Quality of Life Scale (PoCHVAQoLS). Adv Dermatology Allergol. 2015; 32: 143–153.
12. Brzyski P, Chichocka-Jarosz E. Parents’ of Children with Hymenoptera Venom Allergy Quality of Life Scale (PoCHVAQoLS) official webpage. http://www.pochvaqols.cm-uj.kr.... (access: 2015.01.05).
13. Cichocka-Jarosz E, Brzyski P, Tobiasz-Adamczyk B, Lis G, Pietrzyk JJ. Development of children’s hymenoptera venom allergy quality of life scale (CHVAQoLS). Clinical and Translational Allergy. 2013; 3: 25.
14. Cichocka-Jarosz E, Brzyski P. Children’s Hymenoptera Venom Allergy Quality of Life Scale (CHVAQoLS) official webpage. www.chvaqols.cm-uj.krakow.pl. (access: 2015.01.05).
15. Bonifazi F, Jutel M, Biló BM, Birnbaum J, Muller U, EAACI Interest Group on Insect Venom Hypersensitivity. Prevention and treatment ofhymenoptera venom allergy: guidelines for clinical practice. Allergy. 2005; 60: 1459–1470.
16. Tobiasz-Adamczyk B, Brzyski P, Cichocka-Jarosz E. Jakość życia chorych z alergią na jad owadów [Quality of life of patients with venom allergy]. In: Nittner-Marszalska M, editor. Alergia na owady [Insect allergy]. Łódź, Mediton Oficyna Wydawnicza, 2016. p. 105–123.
17. Cichocka-Jarosz E, Tobiasz-Adamczyk B, Brzyski P, Lis G, Jedynak-Wąsowicz U, Pietrzyk JJ, et al. Jakość życia warunkowana stanem zdrowia dzieci z alergią na jad owadów błonkoskrzydłych leczonych VIT oraz jakość życia ich rodziców [Health-related quality of life in children with Hymenoptera venom allergy treated with VIT and quality of life of their parents]. Przegląd Lek. 2010: 12: 1243–1248.
18. Wrześniewski K, Sosnowski T, Jaworowska A, Fecenec D. Inwentarz Stanu i Cechy Lęku STAI. Polska adaptacja STAI. Podręcznik. Warszawa, Pracownia Testów Psychologicznych PTP, 2006.
19. Cichocka-Jarosz E, Brzyski P, Świebocka E, Lange J, Tobiasz-Adamczyk B, Lis G, et al. Health-related quality of life in Polish adolescents with Hymenoptera venom allergy treated with venom immunotherapy. Arch Med Sci. 2012; 6: 1076–1082.
20. Oude-Elberink JNG, de Konchy JGR, Golden DBK, Brouwer J-LP, Guyatt GH, Dubois AEJ, et al. Development and validation of a health-related quality-of-life questionnaire in patients with yellow jacket allergy. J Allergy Clin Immunol. 2002; 1: 162–170.
21. Oude Elberink JNG, Dubois AEJ. Quality of life in insect venom allergic patients. Curr Opin Allergy Clin Immunol. 2003; 3: 287–293.
22. Niedoszytko M, Majkowicz M, Chełmińska M, Buss T, Gruchała-Niedoszytko M, Jassem E. Quality of life, anxiety, depression and satisfaction with life in patients treated with insect venom immunotherapy. Adv Dermatology Allergol. 2012; 2: 74–79.
23. Fischer J, Feidt A, Giel KE, Martens U, Zipfel S, Biedermann T, Teufel M. Quality-of-life in wasp venom allergy – validation of the German version of the “Vespid Allergy Quality of Life Questionnaire” (VQLQ-d). JDDG; 2011; 9: 379–385.
24. Koschel DS, Schmies M, Nink Weber C, Höffken G, Balck F. Tolerated Sting Challenge in Patients on Hymenoptera Venom Immunotherapy Improves Health-Related Quality of Life, J Investig Allergol Clin Immunol. 2014; 24: 226–230.
25. Alfaya T, Vega A, Domínguez-Noche C, Ruiz B, Marqués L, Sánchez-Morillas L. Longitudinal Validation of the Spanish Version of the Health-Related Quality of Life Questionnaire for Hymenoptera Venom Allergy (HRQLHA). J Investig Allergol Clin Immunol. 2015; 25: 426–430.
26. Armisén M, Guspi R, Alfaya T, Cruz S, Fernández S, Domínguez-Noche C, Alonso A, Dalmau G, Marqués L, Vega A. Cross-Sectional Validation of a Quality of Life Questionnaire in Spanish for Patients Allergic to Hymenoptera Venom. J Investig Allergol Clin Immunol. 2015; 25: 107–111.
27. Sin BA, Öztuna D, Gelincik A, Gürlek F, Baysan A, Sin AZ, Aydın Ö, Mısırlıgil Z. Quality-of-life in insect venom allergy: validation of the Turkish version of the “Vespid Allergy Quality of Life Questionnaire” (VQLQ-T), Springer Plus 2016; 5: 583, DOI 10.1186/s40064-016-2246-x.
28. Silva D, Pereira AM, Santo SN, Amaral L, Delgado L, Oude Elberink J.N.G. (H.), Coimbra A. The Vespid Allergy Quality of Life Questionnaire – cultural adaptation and translation to Portuguese. Eur Ann Allergy Clin Immunol. 2017; 49: 114–121.
29. Schumacker RE, Lomax RG. A beginner’s guide to structural equation modelling, Second edition. Mhawah: Lawrence Erlbaum Associates 2004.
eISSN:1898-2263
ISSN:1232-1966