CASE REPORT
Acute respiratory distress syndrome (ARDS) in the course of influenza A/H1N1v infection – genetic aspects
 
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1
Military Institute of Hygiene and Epidemiology, Biological Threat Identification and Countermeasures Centre, Pulawy, Poland
2
BioVectis, Warsaw, Poland; Electron Microscopy Platform, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
3
Department of Expert Medical Assistance with Emergency Medicine Unit, Medical University, Lublin, Poland
4
BioVectis, Warsaw, Poland
5
Department of Internal Medicine, Independent Public Clinical Hospital, Lublin, Poland
 
Ann Agric Environ Med 2013;20(4):711–714
KEYWORDS:
ABSTRACT:
Influenza is a contagious respiratory disease caused by viruses belonging to the family Ortomyxoviridae. Among the influenza viruses type A, B and C, the A type virus shows the most pathogenic potential. Its surface receptor glycoproteins, hemagglutinin (HA) and neuraminidase (NA), are characterized by high antigenic variation, thus a host organism cannot develop permanent resistance. The case is described of a male patient with severe acute respiratory distress syndrome in the course of influenza A/N1H1v infection, confirmed by virological molecular analysis. During diagnostic procedures based on the MSSCP genotyping it was observed that the WHO recommended RT-PCR kits and/or procedure of sample collection from patients for molecular investigation could lead to false positive A/H1N1 pandemic strain detection because of the co-amplification during the RT-PCR fragments of the human genome.
CORRESPONDING AUTHOR:
Katarzyna Naylor   
Department of Expert Medical Assistance with Emergency Medicine Unit, Medical University, Lublin, Poland
 
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