CASE REPORT
A 56-year-old man with RT-PCR negative nasopharyngeal swabs with Coronavirus Disease 2019 (COVID-19) Pneumonia
1
Chair and Department of Infectious Diseases, Medical University, Lublin, Poland
2
Chair and Department of Internal Diseases, Medical University, Lublin, Poland
3
Institute of Rural Health, Lublin, Poland
Corresponding author
Anna Dworzańska
Medical University of Lublin Chair and Department of Infectious Diseases, Staszica 16, 20-081, Lublin, Poland
Medical University of Lublin Chair and Department of Infectious Diseases, Staszica 16, 20-081, Lublin, Poland
Ann Agric Environ Med. 2020;27(2):317-318
KEYWORDS
RT-PCRpneumoniaCOVID-19Coronavirus Disease 2019chest computed tomographyreal-time-reverse transcription-polymerase chain-reaction
TOPICS
Biological agents posing occupational risk in agriculture, forestry, food industry and wood industry and diseases caused by these agents (zoonoses, allergic and immunotoxic diseases)Health effects of chemical pollutants in agricultural areas , including occupational and non-occupational effects of agricultural chemicals (pesticides, fertilizers) and effects of industrial disposal (heavy metals, sulphur, etc.) contaminating the atmosphere, soil and water
ABSTRACT
Introduction:
Diagnostic procedure in Coronavirus Disease 2019 (COVID-19) is based mainly on performing real-time-reverse transcription-polymerase chain-reaction (RT-PCR), which has been accepted as the gold standard method. In some cases, such as mutations of the SARS-CoV-2 genome, variable viral load kinetics or laboratory errors, it can be false-negative.
Case report:
The case is presented of a 56-year-old man with respiratory tract symptoms, with twice negative results of real-time-reverse transcription-polymerase chain-reaction of nasopharyngeal swabs and positive chest computed tomography, with typical findings for COVID-19 pneumonia.
Conclusions:
Patients with negative RT-PCR results, but with positive computed tomography findings characteristic for COVID-19, should be treated as well as those infected.
Diagnostic procedure in Coronavirus Disease 2019 (COVID-19) is based mainly on performing real-time-reverse transcription-polymerase chain-reaction (RT-PCR), which has been accepted as the gold standard method. In some cases, such as mutations of the SARS-CoV-2 genome, variable viral load kinetics or laboratory errors, it can be false-negative.
Case report:
The case is presented of a 56-year-old man with respiratory tract symptoms, with twice negative results of real-time-reverse transcription-polymerase chain-reaction of nasopharyngeal swabs and positive chest computed tomography, with typical findings for COVID-19 pneumonia.
Conclusions:
Patients with negative RT-PCR results, but with positive computed tomography findings characteristic for COVID-19, should be treated as well as those infected.
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