CASE REPORT
Rare case of Richter’s syndrome localization in liver and thyroid of a patient with a chronic lymphocytic leukemia (CLL) – Case report and literature
 
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1
Chair and Department of Haematooncology and Bone Marrow Transplantation, Medical University, Lublin, Poland
2
Department of Clinical Transplantology, Medical University, Lublin, Poland
3
Chair and Department of Neurosurgery and Paediatric Neurosurgery, Medical University, Lublin, Poland
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Chair and Department of Clinical Immunology, Medical University, Lublin, Poland
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Chair and Department of Clinical Pathomorphology, Medical University, Lublin, Poland
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Department of Otolaryngology and Laryngological Oncology, Medical University, Lublin, Poland
CORRESPONDING AUTHOR
Agnieszka Szymczyk   

Chair and Department of Haematooncology and Bone Marrow Transplantation, Medical University of Lublin, Department of Clinical Transplatology, Medical University of Lublin
 
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ABSTRACT
Richter’s syndrome (RS) is a rare complication in which chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) transforms into a more aggressive type of lymphoma – diffuse large B cell lymphoma (DLBCL), or Hodgkin’s lymphoma (HL). The review describes the clinical case of a patient with CLL and RS diagnosis. A computed tomography (CT) scan of the abdominal cavity detected numerous normodense areas in the liver. Simultaneously, ultrasound examination (USG) of the thyroid revealed the presence of a solid hypoechogenic lump. The material sampled from closed biopsies of liver and thyroid in both cases allowed the diagnosis of diffuse large B cell lymphoma (DLBCL). The liver and the thyroid are particularly rare locations of RS. However, those cases allowed the conclusion that RS may occur even in a very unexpected and less probable location.
 
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