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4/2012 vol. 19
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CASE REPORT
Twice malignant transformation of hypertrophic lichen planus
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1
Department of Dermatology, Venereology and Pediatric Dermatology, Medical University, Lublin, Poland
2
Department of Surgical Oncology, Medical University, Lublin, Poland
3
Regional Centre for Blood Donation and Haemotherapy – Local Branch in Zamosc, Poland
CORRESPONDING AUTHOR
Dorota Krasowska   

Department of Dermatology, Venereology and Pediatric Dermatology, Medical University, Lublin, Poland
 
Ann Agric Environ Med. 2012;19(4):787–789
 
Article (PDF)
References (27)
 
KEYWORDS
autoimmune disease
lichen planus
malignant transformations
squamous cell carcinoma
 
ABSTRACT
Lichen planus is a chronic mucocutaneous T-cell-mediated disease, the cause of which remains unknown. The first case of lichen planus that transformed into squamous cell carcinoma was reported in 1903. The presented study concerns the case of a 62-year-old woman in whom twice malignant transformation of hypertrophic lichen planus in the dorsal part of the left foot developed. Several studies have pointed out the malignant transformation potential of lichen planus. Epidemiological studies from the last 20 years have revealed a malignant transformation rate of 0.27% per year, emphasizing the importance of the clinical follow-up of lichen planus patients.
 
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