RESEARCH PAPER
Impact of copper (Cu) at the dose of 50 mg on haematological and biochemical blood parameters in turkeys, and level of Cu accumulation in the selected tissues as a source of information on product safety for consumers
 
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1
Chair of Biochemistry and Toxicology, Department of Breeding and Pig Production, University of Life Sciences, Lublin, Poland
2
Department of Alergology and Environmental Hazards, Institute of Rural Health, Lublin, Poland
3
University of Life Sciences, Lublin, Poland
 
Ann Agric Environ Med. 2014;21(3):567–570
KEYWORDS
ABSTRACT
Introduction:
The current state-of the art points to a positive impact of copper (Cu) supplements on the general health status in poultry. Copper induces beneficial changes in the haematological and biochemical blood parameters. It also displays immunostimulating properties and helps maintain a proper microbiological balance in the digestive tract.

Objective:
The objective of this study was to investigate the impact of Cu at the dose of 50 mg/kg BW, administered in organic and inorganic form, on the haematological and biochemical blood parameters and level of Cu bioaccumulation in the liver and pectoral muscle.

Material and Methods:
The study was carried out on 45 BUT-9 turkeys which had been were reared for 16 weeks. They were divided into 3 experimental groups: I – the control group; II – fed with CuSO4 at the dose of 50 mg Cu•dm-3 H2O; III – received a Cu chelate with lysine at the same dose.

Results:
The administration of Cu at the dose exceeding the nutritional recommendations did not induce beneficial changes in the examined birds. This indicates that it is not necessary to administer Cu doses higher than the recommended levels. The extent of Cu accumulation in the pectoral muscle increased by 40% compared to the control group, whereas in the liver it was higher by 30–35% than in the birds without Cu administration. The level of Cu in tissues does not pose a risk to consumers.

 
REFERENCES (27)
1.
Makarski B, Gortat M. Effect of supplementation with copper in different chemical forms on selected physiological blood markers and content of minerals in selected tissues of turkeys. J Elem. 2011; 16 (4): 591–602.
 
2.
Abdallah AG, El-Husseiny OM, Abdel – Latif KO. Influence of Some Dietary Organic Mineral Supplementations on Broiler Performance. J Poult. Sci. 2009; 8(3): 291–298.
 
3.
Kuźlik-Wyrostek M, Makarski B. Effect of Cu and lactic acid on hematological and biochemical blond indices and on modification of microbial flora in the gastrointestinal tract of turkeys. J Elem. 2009; 14 (3): 53.
 
4.
Hordyjewska A, Pasternak K. Miedź. In: Jackowska I. Pierwiastki w środowisku i medycynie. Wyd. Instytut Naukowo – Wydawniczy SPATIUM. 2011.p.415–432 (in Polish).
 
5.
Wanga Z, Cerrate S, Yan F, Sacakli P, Waldroup PW. Comparison of Different Concentrations of Inorganic Trace Minerals in Broiler Diets on Live Performance and Mineral Exeretion. Int J Poult Sci. 2008; 7(7): 625–629.
 
6.
Pesti GM, Bakalii RI. Studies on the feeding of cupric sulfate pentahydrate and cupric citrate to broiler chickens. Poult Sci. 1996; 75: 1086–1091.
 
7.
Doerr JA, Nicholson JL, Johnson E. Influence of dietary copper on litter quality and broiler performance. Proc Maryland Nutr Conf. 1980; 61–65.
 
8.
Fisher C, Laursen-Jones AP, Hill KJ, Hardy WS. The effect of copper sulphate on performance and structure of the gizzard in broilers. Br Poult Sci. 1973; 14: 55–68.
 
9.
Jankins NK, Morris TR, Valamotis D. The effect of diet and copper supplementation on chick growth. Br Poult Sci. 1970; 11: 241–248.
 
10.
Aoyagi S, Baker DH. Nutritional evaluation of copper-lysine and zinclysine complexes for chickens. Poul Sci. 1993; 72: 165–171.
 
11.
Guo R, Henry PR, Holwerda RA, Cao J, Littell RC, Miles RD, et al. Chemical characteristics and relative bioavailability of supplemental organic copper sources for poultry. J Anim Sci. 2001; 79: 1132–1141.
 
12.
Bao YM, Choct M, Iji PA, Bruerton K. Effect of Organically Completed Copper, Iron, Manganese and Zinc on Broiler Performance, Mineral Excretion and Accumulation in Tissues. J Appl Poult Res. 2007; 16: 448–455.
 
13.
Paik IK, Seo SH, Um JS, Chang MB, Lee BH. Effect of supplementary copper-chelate on the performance and cholesterol level in plasma and pectoral muscle of broiler chicks. Asian-Aust. J Anim Sci. 1999; 12: 794–798.
 
14.
National Research Council. Nutrient Requirements of Poultry. 9th rev. ed. Washington. National Academy Press. 1994.
 
15.
Waldroup PW, Fritts CA, Fenglan Y. Utilization of Bio-MOS® Mannan Oligosaccharide and Bioplex® Copper in Broiler Diets. Int J Poult Sci. 2003; 2(1): 44–52.
 
16.
Noy Y, Frisch Y, Rand N, Sklan D. Trace mineral requirements in turkeys. World’s Poult Sci. 1994; 50: 253–268.
 
17.
Faruga A, Jankowski J. Turkeys – breed and harnessing. Warszawa. PWRiL, 1996. 18. Smulikowska S, Rutkowski A. Nutrient Requirments of Poultry. 4th rev. ed. Jabłonna The Kielanowski Institute of Animal Physiology and Nutrition PAS, 2005 (in Polish).
 
18.
Smulikowska S. Polutry nutrition standards. Warszawa. PAN, 1996 (in Polish).
 
19.
Dmoch M, Polonis A. Wpływ biopleksu miedziowego na wybrane wskaźniki hematologiczne, biochemiczne i zawartość składników mineralnych w krwi kurcząt brojlerów. Acta Sci Pol. 2007; 6(3): 11–18 (in Polish).
 
20.
Sevcikova S, Skrivan M, Skrivanova V, Tumowa E, Koucky M. Effect of suplementation of copper in copper sulphate and Cu-glicine on fatty acid profile in meat of broiler chickens, colesterol content and oxidation stability of fat. Czech J Anim Sci. 2003; 48(10): 432–440.
 
21.
Makarski B, Polonis A. Effect of bioplex – Cu on the level of biochemical indices of turkey blood. Pol J Food Nutr Sci. 2001; 10/51(1): 49–51.
 
22.
Tapiero H, Townsend DM, Tew KD. Trace elements in human physiology and pathology. Copper Biomed Pharmacother. 2003; 57: 386–398.
 
23.
Thiele DJ. Intergrating trace element metabolism from the cell to the whole organism. J Nutr. 2003; 133: 1579–1580.
 
24.
Mikulski D, Jankowski J, Zduńczyk Z, Wróblewska M, Mikulska M. Cooper balance, bone mineralization and the growth performance of turkeys fed diet with two types of Cu supplements. J Anim Feed Sci. 2009; 18: 677–688.
 
25.
Igbasan FA, Akinsanmi SK. Growth response and carcass quality of broiler chickens fed on diets supplemented with dietary copper sources. Afr J Agric Res. 2012; 7(11):1674–1681.
 
26.
Lim KS, You SJ, An BK, Kang CW. Effects of Dietary Garlic Powder and Copper on Cholesterol Content and Quality Characteristics of Chicken Eggs. Asian-Aust J Anim Sci. 2006; 19(4): 582–586.
 
27.
Yang XJ, Sun XX, Li CY, Wu XH, Yao JH. Effects of copper, iron, zinc and manganese supplementation in a corn and soybean diet on the growth performance, meat, quality and immune responses of broiler chickens. J Appl Poult Res. 2011; 20 (3): 263–271.
 
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