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REVIEW PAPER
 
 

Benefits and risks associated with genetically modified food products

Marta Kramkowska 1  ,  
 
1
Department of Chemistry and Clinical Biochemistry, University of Medical Sciences, Poznan, Poland
Ann Agric Environ Med 2013;20(3):413–419
KEYWORDS:
ABSTRACT:
Scientists employing methods of genetic engineering have developed a new group of living organisms, termed ‘modified organisms’, which found application in, among others, medicine, the pharmaceutical industry and food distribution. The introduction of transgenic products to the food market resulted in them becoming a controversial topic, with their proponents and contestants. The presented study aims to systematize objective data on the potential benefits and risks resulting from the consumption of transgenic food. Genetic modifications of plants and animals are justified by the potential for improvement of the food situation worldwide, an increase in yield crops, an increase in the nutritional value of food, and the development of pharmaceutical preparations of proven clinical significance. In the opinions of critics, however, transgenic food may unfavourably affect the health of consumers. Therefore, particular attention was devoted to the short- and long-lasting undesirable effects, such as alimentary allergies, synthesis of toxic agents or resistance to antibiotics. Examples arguing for the justified character of genetic modifications and cases proving that their use can be dangerous are innumerable. In view of the presented facts, however, complex studies are indispensable which, in a reliable way, evaluate effects linked to the consumption of food produced with the application of genetic engineering techniques. Whether one backs up or negates transgenic products, the choice between traditional and non-conventional food remains to be decided exclusively by the consumers.
CORRESPONDING AUTHOR:
Marta Kramkowska   
Department of Chemistry and Clinical Biochemistry, University of Medical Sciences, Poznan, Poland
 
REFERENCES:
1. Latifah A, Fadhli H, Roosfa H, Mus CS, Nurina A, Zinatul ZA, et al. Risks and benefits of genetically modified foods. Afr J Biotechnol. 2011; 10(58): 12481–12485.
2. Linkiewicz A, Wiśniewska I, Sowa S. Molekularne metody wykrywania i identyfikacji organizmów genetycznie zmodyfikowanych (GMO). Biotechnologia. 2006; 3(74): 44–52 (in Polish).
3. Wrześniewska-Wal I. Prawne aspekty wprowadzania do obrotu żywności genetycznie zmodyfikowanej. Post Nauk Med. 2009; 4: 310–315 (in Polish).
4. Lemaux P. Genetically engineered plants and foods: A scientist’s analysis of the issue (part 1). Annu Rev Plant Biol. 2008; 59: 771–812.
5. Kolasa-Więcek A. Organizmy modyfikowane genetycznie – próba oceny świadomości społeczeństwa polskiego. Post Tech Przetw Spoż. 2008; 2: 57–59 (in Polish).
6. Qaim M. The economics of genetically modified crops. Annu Rev Resour Econ. 2009; 1: 665–693.
7. Ochocki Z, Stańczak A. Organizmy genetycznie zmodyfikowane – żywność i leki przyszłości? Część I i II. Farm Pol. 2005; 61(8): 361–377 (in Polish).
8. Maghari BM, Ardekani AM. Genetically modified foods and social concerns. Avicenna J Med Biotech. 2011; 3(3): 109–117.
9. Hug K. Genetically modified organisms: Do the benefits outweigh the risks? Medicina (Kaunas). 2008; 44(2): 87–99.
10. Greene C, Smith C. Can genetically engineered and organic crops coexist? Choices. 2010; 25(2): 1–6.
11. Scholtens I, Kok E, Hougs L, Molenaar B, Thissen J, van der Voet H. Increased efficacy for in-house validation of real time PCR GMO detection methods. Anal Bioanal Chem. 2010; 396: 2213–2227.
12. Sisea C, Pamfil D, Pop J, Petricele I, Raica P, Ciuzan O. GMO testing for the presence of Roundup ready soybean. Rom Biotechnol Lett. 2010; 15(1): 34–44.
13. Morris S, Spillane C. GM directive deficiencies in the European Union. EMBO reports. 2008; 9(6): 500–504.
14. Tait J. Risk governance of genetically modified crops – European and American perspectives. In: Renn O, Walker KD. Global Risk Governance. Geneva 2008.p.133–153.
15. Pandey A, Kamle M, Yadava LP, Muthukumar M, Kumar P, Gupta V, et al. Genetically modified food: Its uses, future prospects and safety assessments. Biotechnology. 2011; 10(5): 473–487.
16. Morin X. Genetically modified food from crops: Progress, pawns and possibilities. Anal Bioanal Chem. 2008; 392: 333–340.
17. Raport International Service for the Acquisition of Agri-Biotech Applications: Kraje rozwijające się prowadzą w światowej uprawie roślin GM – raport ISAAA. Rolniczy Magazyn Elektroniczny. 2012; 51, http://rme.cbr.net.pl/index.php?option=com_content&view=article&id=258:krajerozwijajce-si-prowadz-w-wiatowej-uprawie-rolin-gm--raport-isaaa&catid=108:-rolnictwo-w-uni-europejskiej&Itemid=119 (access: 4.10.2012) (in Polish).
  WWW
18. Qaim M. Benefits of genetically modified crops for the poor: Household income, nutrition, and health. New Biotechnol. 2010; 27(5): 552–557.
19. Kondratowicz J, Burczyk E, Dąbrowska P. Żywność genetycznie modyfikowana – szanse i zagrożenia dla konsumentów. Chłodnictwo. 2009; 9: 52–57 (in Polish).
20. Kosicka-Gębska M, Gębski J. Oczekiwania i obawy związane z wprowadzaniem do obrotu produktów i żywności pochodzących z genetycznych modyfikacji. Problemy Rolnictwa Światowego. Zeszyty Naukowe SGGW w Warszawie. 2009; 9: 65–76 (in Polish).
21. Mickiewicz A, Twardowski T, Figlarowicz M. GMO – zyski i straty. Biotechnologia. 2006; 3(74): 145–153 (in Polish).
22. Yonekura K, Saito K. Review: Genetically modified plants for the promotion of human health. Biotechnol Lett. 2006; 28: 1983–1991.
23. Key S, Ma JK, Drake PM. Genetically modified plants and human health. J R Soc Med. 2008; 101: 290–298.
24. Falk MC, Chassy BM, Harlander SK, Hoban TJ IV, McGloughlin MN, Akhlaghi AR. Food biotechnology: Benefits and concerns. J Nutr. 2002: 132; 1384–1390.
25. Duliński R. Biotechnologiczne metody produkcji witamin z wykorzystaniem mikroorganizmów. Żyw Nauka Technol Jakość. 2010; 1(68): 5–19 (in Polish).
26. Nowicka G. Żywność zmodyfikowana genetycznie i jej wpływ na zdrowie. Zdr Publ. 2005; 115(2): 226–231 (in Polish).
27. European Molecular Biology Organization. GM plants for your health. Science and Society. 2004; 5: 1031–1034.
28. Bednarski W, Repsa A. Biotechnologia żywności. In: Bednarski W. Biotechnologia pozyskiwania żywności. Wydawnictwo Naukowo-Techniczne, Warszawa 2003.p.238–262 (in Polish).
29. Twardowski T. Chances, perspectives and dangers of GMO in agriculture. J Fruit Ornam Plant Res. 2010; 18(2): 63–69.
30. Bagwan JD, Patil SJ, Mane AS, Kadam VV, Vichare S. Genetically modified crops: food of the future (review). Int J Adv Biotechnol Res. 2010; 1(1): 21–30.
31. Zeeman SC, Kossmann J, Smith AM. Starch: Its metabolism, evolution, and biotechnological modification in plants. Annu Rev Plant Biol. 2010; 61: 209–34.
32. Cruz-Hernandez A, Paredes-Lopez O. Fruit quality: new insights for biotechnology. Crit Rev Food Sci Nutr. 2012; 52: 272–289.
33. Kumar S, Chandra A, Pandey KC. Bacillus thuringiensis (Bt) transgenic crop: An environment friendly insect-pest management strategy. J Environ Biol. 2008, 29(5): 641–653.
34. Tyczewska A, Twardowski T. Organizmy genetycznie zmodyfikowane, za i przeciw. Bromat Chem Toksykol. 2008; 3: 197–201 (in Polish).
35. Ronald P. Plant genetics, sustainable agriculture and global food security. Genetics. 2011; 188: 11–20.
36. Cichocki M, Baer-Dubowska W. Organizmy transgeniczne w farmacji i medycynie. Wydawnictwo Naukowe Akademii Medycznej im. Karola Marcinkowskiego w Poznaniu, 2006 (in Polish).
37. Ostaszewska I, Sablik P. Biotechnologiczne metody doskonalenia zwierząt hodowlanych jako źródła żywności o zwiększonej zawartości kwasów tłuszczowych. Biotechnologia. 2008; 3(82): 153–158 (in Polish).
38. Ubalua A. Transgenic plants: Successes and controversies. Biotechnol Mol Biol Rev. 2009; 4(6): 118–127.
39. Verma C, Nanda S, Singh RK, Singh R.B Sanjay S. A review on impacts of genetically modified food on human health. Open Nutraceuticals J. 2011; 4: 3–11.
40. Maruyama N, Mikami B, Utsumi S. The development of transgenic crops to improve human health by advanced utilization of seed storage proteins. Biosci Biotechnol Biochem. 2011; 75(5): 823–828.
41. Clark J, Whitelaw BA. Future for transgenic livestock. Nature Rev Genet. 2003; 4: 825–833.
42. Niemann H, Lucas-Hahn A. Somatic cell nuclear transfer cloning: Practical applications and current legislation. Reprod Dom Anim. 2012; 47: 2–10.
43. Niemann H, Kues W, Carnwath JW. Transgenic farm animals: Present and future. Rev Sci Tech Off Int Epiz. 2005; 24 (1): 285–298.
44. Lisowska K, Chorąży M. Genetycznie zmodyfikowane uprawy i żywność – przegląd zagrożeń. Nauka. 2010; 4: 127–136 (in Polish).
45. Domingo JL. Toxicity studies of genetically modified plants: A review of the published literature. Crit Rev Food Sci Nutr. 2007; 47: 721–733.
46. Ekici K, Can Sancak Y. A perspective on genetically modified food crops. Afr J Agric Res. 2012; 6(7): 1639–1642.
47. Bernstein JA, Bernstein LI, Bucchini L, Goldman LR, Hamilton RG, Lehrer S, et al. Clinical and laboratory investigation of allergy to genetically modified foods. Environ Health Perspect. 2003; 111(8): 1114–1121.
48. Ladics GS, Cressman RF, Herouet-Guicheney C, Herman RA, Privalle L, Song P, et al. Bioinformatics and the allergy assessment of agricultural biotechnology products: Industry practices and recommendations. Regul Toxicol Pharmacol. 2011; 60: 46–53.
49. D’Agnolo G. GMO: Human health risk assessment. Vet Res Comm. 2005; 29: 7–11.
50. Dona A, Arvanitoyannis IS. Health risk of genetically modified foods. Crit Rev Food Sci Nutr. 2009; 49: 164–175.
51. Batista R, Oliveira MM. Facts and fiction of genetically engineered food. Trends Biotechnol. 2009; 27(5): 277–286.
52. Wiąckowski SK. Żywność genetycznie modyfikowana a problem alergii. Prz Lek. 2004; 61: 22–24 (in Polish).
53. Suarez A, Viloria MD, Garcia-Barreno R, Municio AM. Toxic oil syndrome, Spain: effect of oleoylanilide on the release of polysaturated fatty acids and lipid peroxidation in rats. Arch. Environ. Contam Toxicol. 1985; 14: 131–136.
54. Quero C, Colomé N, Rodriguez C, Eichhorn P, Posada de la Paz M, Gelpi E, et al. Proteomics of toxic oil syndrome in humans: Phenotype distribution in a population of patients. Chem Biol Interact. 2011; 192(1–2): 129–135.
55. Spiroux de Vendômois J, Roullier F, Cellier D, Séralini GE. A comparison of the effects of three GM corn varieties on mammalian health. Int J Biol Sci. 2009; 5(7): 706–726.
56. Spiroux de Vendômois J, Cellier D, Vélot C, Clair E, Mesnage R, Séralini GE. Debate on GMOs health risks after statistical findings in regulatory tests. Int J Biol Sci. 2010; 6(6): 590–598.
57. Séralini GE, Clair E, Mesnage R, Gress S, Defarge N, Malatesta M, et al. Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food Chem Toxicol. 2012; 50: 4221–4231.
58. Duke SO, Rimando AM, Pace PF, Reddy KN, Smeda RJ. Isoflavone, glyphosate, and aminomethylphosphonic acid levels in seeds of glyphosate-treated, glyphosate-resistant soybean. J Agric Food Chem. 2003; 51: 340–344.
59. Magańa-Gómez JA, Calderón de la Barca A. Risk assessment of genetically modified crops for nutrition and health. Nutr Rev. 2009; 67(1): 1–16.
60. Om VS, Shivani G, Debarati P, Rakesh KJ. Genetically modified crops: Success, safety assessment and public concern. Appl Microbiol Biotechnol. 2006; 71: 598–607.
61. Craig W, Tepfer M, Degrassi G, Ripandelli D. An overview of general features of risk assessment of genetically modified crops. Euphytica. 2008; 164: 853–880.
62. Paoletti C, Flamm E, Yan W, Meek S, Renckens S, Fellous M, et al. GMO risk assessment around the world: Some examples. Trends Food Sci Technol. 2008; 19: S70-S78.
63. Azadi H, Ho P. Genetically modified and organic crops in developing countries: A review of options for food security. Biotechnol Adv. 2010; 28: 160–168.
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