RESEARCH PAPER
Wild and farm breeding cervids infections with Anaplasma phagocytophilum.
Branislav Pet'ko
2,3
| 1 | W. Stefański Institute of Parasitology of the Polish Academy of Sciences, Warsaw, Poland |
| 2 | Parasitological Institute of the Slovak Academy of Sciences, Košice, Slovakia |
| 3 | Faculty of Natural Sciences Comenius University, Bratislava, Slovakia |
Ann Agric Environ Med. 2011;18(1):73–77
KEYWORDS
ABSTRACT
The main goal of our study was to determine the prevalence of Anaplasma phagocytophilum infections in wild cervids living in north-eastern part of Poland. Material used in the study was gathered between the years 2004- 2008. The blood samples from 106 red deer (Cervus elaphus), 32 sika deer (Cervus nippon hortulorum), 130 fallow deer (Dama dama) and 31 roe deer (Capreolus capreolus) were collected. DNA was isolated using Genomic Mini AX blood kit (A and A Biotechnology). Molecular detection of A. phagocytophilum was based on nested PCR amplification of a species-specific 16S rRNA fragment gene of A. phagocytophilum. The highest prevalence of infection was detected in Cervus elaphus, Capreolus capreolus, Cervus nippon hortulorum, there were 50.9 percent, 38.7 percent, 34.37 percent of infected animals, respectively. The lowest rate of infection was found in fallow deer (Dama dama) - ony 1.5 percent.
REFERENCES (50)
1.
Adamska M, Skotarczak B: Wild game as a reservoir of Anaplasma phagocytophilum in north-western Poland. Wiad Parazytol 2007, 53, 103–107.
2.
Alberdi MP, Walker AR, Urquhart KA: Field evidence that roe deer (Capreolus capreolus) are a natural host for Ehrlichia phagocytophila. Epidemiol Infect 2000, 124, 315–323.
3.
Alberti A, Zobba R, Chessa B, Addis MF, Sparagano O, Pinna Parpaglia ML, Cubeddu T, Pintori G, Pittau M: Equine and canine Anaplasma phagocytophilum strains isolated on the island of Sardinia (Italy) are phylogenetically related to pathogenic strains from the United States. Appl Environ Microbiol 2005, 71, 6418–6422.
4.
Barbet AF, Lundgren AM, Alleman AR, Stuen S, Bjöersdorff A, Brown RN, Drazenovich NL, Foley JE: Structure of the expression site reveals global diversity in MSP2 (P44) variants in Anaplasma phagocytophilum. Infect Immun 2006, 74, 6429–6437.
5.
Bednorz E: Changes in snow cover occurrence in northern Germany in winters 1950/51–1999/00. In: Piotrowicz K, Twardosz R (Eds): Wahania klimatu w różnych skalach przestrzennych i czasowych, 215–223, IGiGP UJ, Kraków 2007.
6.
Belongia EA, Reed KD, Mitchell PD, Mitchell PD, Kolbert CP, Persing DH, Gill JS, Kazmierczak JJ: Prevalence of granulocytic Ehrlichia infection among white-tailed deer in Wisconsin. J Clin Microbiol 1997, 35, 1465–1468.
7.
Bray DP, Bown KJ, Stockley P, Hurst JL, Benett M: Haemoparasites of common shrews (Sorex araneus ) in Northwest England. Parasitology 2007, 134, 819–826.
8.
Carpi G, Bertolotti L, Pecchioli E, Cagnacci F, Rizzoli A: Anaplasma phagocytophilum groEL gene heterogenity in Ixodes ricinus larvae feeding on roe deer in Northeastern Italy. Vector Borne Zoonotic Dis 2000, 9, 179–184.
9.
Chen SM, JS, Bakken JS, Walker DH: Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease. J Clin Microbiol 1994, 32, 589–595.
10.
Czarkowski MP, Cielebąk E, Stępień E, Kondej B: Choroby zakaźne i zatrucia w Polsce w 2000 roku. PZH & GIS, Warszawa 2001.
11.
Czarkowski MP, Cielebąk E, Dacka P, Kondej B: Choroby zakaźne i zatrucia w Polsce w 2007 roku. PZH & GIS, Warsaw 2008.
12.
De La Fuente J, Naranjo V, Ruiz-Fons F, Höfle U, Fernández de Mera IG, Villanúa D, Almazán C, Torina A, Caracappa S, Kocan KM, Gortázar C: Potential vertebrate reservoir hosts and invertebrate vectors of Anaplasma marginale and A. phagocytophilum in central Spain. Vector Borne Zoonotic Dis 2005, 5, 390–401.
13.
De la Fuente J, Ruiz-Fons F, Naranjo V, Torina A, Rodriquez O, Gortázar C: Evidence of Anaplasma infections in European roe deer (Capreolus capreolus) from southern Spain. Res Vet Sci 2008, 84, 382–386.
14.
Dumler JS, Barbet AF, Bekker CPJ, Dasch GA, Palmer GH, Ray SC, Rikihisa Y, Rurangirwa FR: Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and ‘HGE agent’ as subjective synonyms of Ehrlichia phagocytophila. Int J Syst Evol Microbiol 2001, 51, 2145–2165.
15.
Falarz M: Variability and trends in the duration and depth of snow cover in Poland in the 20th century. Int J Climatol 2004, 24, 1713–1727.
16.
Foley JE, Barlough JE, Kimsey RB, Madigan JE, Derocke E, Poland A: Ehrlichia spp. in cervids from California. J Wildl Dis 1998, 34, 731–737.
17.
Gage KL, Burkot TR, Eisen RJ, Hayes EB: Climate and Vectorborne Diseases. Am J Prev Med 2008, 35, 436–450.
18.
Gordon WS, Brownlee A, Wilson DR, MacLeod J: Tick-borne fever (a hitherto undescribed disease of sheep). J Comp Pathol 1932, 45, 301–212.
19.
Groen J, Koraka P, Nur YA, Avsic-Zupanc T, Goessens WH, Ott A, Osterhaus AD: Serologic evidence of ehrlichiosis among humans and wild animals in The Netherlands. Eur J Clin Microbiol Infect Dis 2002, 21, 46–49.
20.
Grzeszczuk A, Karbowiak G, Ziarko S, Kovalchuk O: The Rootvole Microtus oeconomus (Pallas, 1776): a new potential reservoir of Anaplasma phagocytophilum. Vector Borne Zoonotic Dis 2006, 6, 240–243.
21.
Grzeszczuk A, Stańczak J, Kubica-Biernat B: Serogical and molecular evidence of human granulocytic ehrlichiosis focus in Białowieża Primeval Forest, northeastern Poland. Eur J Clin Microbiol Infect Dis 2002, 21, 6–11.
22.
Grzeszczuk A, Ziarko S, Prokopowicz D, Radziwoń PM: Zakażenie żubrów z Puszczy Białowieskiej bakteriami Anaplasma phagocytophilum. Med Wet 2004, 60, 600–601.
23.
Humair PF, Douet V, Morán Cadenas F, Schouls LM, Van De Pol I, Gern L: Molecular identification of bloodmeal source in Ixodes ricinus ticks using 12S rDNA as a genetic marker. J Med Entomol 2007, 44, 869–880.
24.
Karbowiak G, Víchová B, Majláthová V, Hapunik J, Pet’ko B: Anaplasma phagocytophilum infection of red foxes (Vulpes vulpes). Ann Agric Environ Med 2009, 16, 299–300.
25.
Kawahara M, Rikihisa Y, Lin Q, Isogai E, Tahara K, Itagaki A, Hiramitsu Y, Tajima T: Novel genetic variants of Anaplasma phagocytophilum, Anaplasma bovis, Anaplasma centrale and a novel Ehrlichia sp. in wild deer and ticks on two major islands in Japan. Appl Environ Microbiol 2006, 72, 1102–1109.
26.
Lin Q, Rikihisa Y, Felek S, Wang X, RF, Woldehiwet Z: Anaplasma phagocytophilum has a functional msp2 gene that is distinct from p44. Infect Immun 2004, 72, 3883–3889.
27.
Little S, Stalljnecht DE, Lockhart JM, Dawson JE, Davidson WR: Natural coinfection of a white-tailed deer (Odocoileus virginianus) population with three Ehrlichia spp. J Parasitol 1998, 84, 897–901.
28.
Liz JS, Andersen L, Sumner JW, RF, Gern L, Rutti B, Brossard M: PCR detection of granulocytic Ehrlichiae in Ixodes ricinus ticks and wild small mammals in western Switzerland. J Clin Microbiol 2000, 38, 1002–1007.
29.
Liz JS, Sumner JW, Pfister K, Brossard M: PCR detection and serological evidence of granulocytic Ehrlichia infection in roe deer (C. capreolus) and chamois (Rupicapria rupicapria). J Clin Microbiol 2002, 40, 892–897.
30.
Massung RF, Courtney JW, Hiratzka SL, Pitzer VE, Smith G, Dryden RL: Anaplasma phagocytophilum in white-tailed deer. Emerg Infect Dis 2005, 11, 1604–1606.
31.
Massung RF, Slater KG: Comparison of PCR assays for detection of the agent of human granulocytic ehrlichiosis, Anaplasma phagocytophilum. J Clin Microbiol 2003, 41, 717–722.
32.
Michalik J, Stańczak J, Racewicz M, Cieniuch S, Sikora B, SzubertKruszyńska A, Grochowalska R: Molecular evidence of Anaplasma phagocytophilum infection in wild cervids and feeding Ixodes ricinus ticks from west-central Poland. In: 5th International Conference on Rickettsiae and Rickettsial Diseases, 18-20 May 2008: 70. Marseille 2008.
33.
Morissette E, Massung RF, Foley JE, Alleman AR, Foley P, Barbet AF: Diversity of Anaplasma phagocytophilum strains, USA. Emerg Infect Dis 2000, 15, 928–931.
34.
Nováková M, Víchová B, Majláthová V, Lesňáková A, Pochybová M, Peťko B: First case of human granulocytic anaplasmosis from Slovakia. Ann Agric Environ Med 2010, 17, 173–175.
35.
Ogden NH, Bown K, Horrocks BK, Woldehiwet Z, Bennett M: Granulocytic Ehrlichia infection in ixodid ticks and mammals in woodlands and uplands of the U.K. Med Vet Entomol 1998, 12, 423–429.
36.
Petrovec M, Bidovec A, Sumner JW, Nicholson WL, Childs JE, Avšič-Županc T: Infection with Anaplasma phagocytophila in cervids from Slovenia: Evidence of two genotypic lineages. Wien Klin Wochenschr 2002, 114/13, 641–647.
37.
Polin H, Hufnagl P, Haunschmid R, Gruber F, Ladurner G: Molecular evidence of Anaplasma phagocytophilum in Ixodes ricinus ticks and wild animals in Austria. J Clin Microbiol 2004, 42, 2285–2286.
38.
Prokopowicz D: Choroby przenoszone przez kleszcze. Wydawnictwa Fundacji Büchnera, Warsaw 1995.
39.
Siuda K: The review of data on the distribution of Ixodida (Acari) in Poland. In: Kropczyńska D, Boczek J, Tomczyk A (Eds): The acari: Physiological and ecological aspects of acari-host relationships, 273- 280, Oficyna Dabor, Warsaw 1995.
40.
Smetanová K, Schwarzová K, Kocianová E: Detection of Anaplasma phagocytophilum, Coxiella burnetii, Rickettsia spp., and Borrelia burgdorferi s.l. in ticks, and wild-living animals in western and middle Slovakia. Ann NY Acad Sci 2006, 1078, 312–315.
41.
Stańczak J, Racewicz M, Kruminis-Łozowska W, Kubica-Biernat B: Coinfection of Ixodes ricinus (Acari: Ixodidae) in northern Poland with the agents of Lyme Boreliosis (LB ) and human granulocytic ehrlichiosis (HGE ). Int J Med Microbiol 2002, 291, 198–2001.
42.
Stefanidesova K, Kocianova E, Boldis V, Kostanova Z, Kanka P, Nemethova D, Spitalska E: Evidence of Anaplasma phagocytophilum and Rickettsia helvetica infection in free-ranging ungulates in central Slovakia. Eur J Wildl Res 2008, 54, 519–524.
43.
Stuen S: Anaplasma phagocytophilum- the most widespread tickborne infection in animals in Europe. Vet Res Commun 2007, 31 (Suppl. 1), 79–84.
44.
Stuen S, Akerstedt J, Bergstrom K, Handeland K: Antibodies to granulocytic Ehrlichia in moose, red deer, and roe deer in Norway. J Wildl Dis 2002, 38, 1–6.
45.
Tylewska-Wierzbanowska S, Chmielewski T, Kondrusik M, Hermanowska-Szpakowicz T, Sawicki W, Sułek K: First cases of acute human granulocytic ehrlichiosis in Poland. Eur J Clin Microbiol Inf 2001, 20, 196–198.
46.
Walls JJ, Asanovich KM, Bakken JS, Dumler JS: Serologic evidence of a natural infection of white-tailed deer with the agent of human granulocytic ehrlichiosis in Wisconsin and Maryland. Clin Diagn Lab Immunol 1998, 5, 762–765.
47.
Welc-Falęciak R, Hildebrandt A, Siński E: Co-infection with Borrelia species and other tick-borne pathogens in humans: two cases from Poland. Ann Agric Environ Med 2010, 17, 309–313.
48.
Woldehiwet Z: Anaplasma phagocytophilum in Ruminants in Europe. Ann NY Acad Sci 2006, 1078, 446–460.
49.
Zeman P, Pecha M: Segregation of genetic variants of A. phagocytophilum circulating among wild ruminants within a Bohemia forest (Czech Republic). Int J Med Microbiol 2008, 298, 203–210.
50.
Zwoliński J, Chmielewska-Badora J, Wójcik-Fatla A, Cisak E, Buczek A, Dutkiewicz J: Anaplazmoza granulocytarna jako nowy problem zdrowia publicznego. Zdr Publ 2007, 117, 213–219.
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