Calcium and vitamin D supply in Polish population – facts and myths
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Department of Endocrinology and Metabolic Diseases, Polish Mother’s Memorial Hospital – Research Institute, Medical Univerity of Lodz, Poland
Ann Agric Environ Med. 2014;21(3):455-456
Traditionally, calcium and vitamin D are treated as partners crucial for bone health. In the human body calcium is located mostly in the skeleton, only 1–2% is present in body fluids and this part is metabolically active. Serum calcium concentration is closely regulated within a narrow physiological range [1]. However, calcium is responsible not only for bone mineralization but also for muscular and neural conductivity and blood coagulation [1]. Vitamin D is necessary for calcium absorption, through amplification of calbindin synthesis, it is also involved in the regulation of parathyroid hormone synthesis [1, 2]. Recently, the pleiotropic effects of vitamin D have become the subject of interest [1, 2]; potential extraskeletal benefits of vitamin D intake include lower cardiovascular morbidity and mortality, reduced risk of diabetes mellitus, breast and colon cancer, multiple sclerosis, allergy, asthma and cognitive illness [1, 2, 3]. Calcium and vitamin D deficiency may lead to secondary hyperparathyroidism which results in the development of rickets and low peak bone mass in children and processes of osteomalacia and osteoporosis in adults [2]. Low vitamin D status in women is associated with impaired fertility [4], adverse pregnancy outcomes, such as miscarriage, preeclampsia and preterm birth, development of gestational diabetes and bacterial vaginosis [4, 5]. Vitamin D deficiency in pregnant women may affect their offspring, because there is a strong correlation between maternal and cord blood 25(OH)D and newborns have inadequate vitamin D storage to draw on in early life [6]. Vitamin D affects more than 3,000 genes, many of which have a role to play in foetal development [7], supporting hypothesis on the role of vitamin D in foetal programming, influencing the genomic programming of foetal and neonatal development, and subsequent disease risk of respiratory infections and asthma, type-1 diabetes and schizophrenia in both childhood and adult life [8, 9]. Rickets, low bone mineral density and reduced postnatal linear growth and weight gain may also occur, particularly if the postnatal supplementation of vitamin D is not sufficient [9]. Diet is the main source of calcium for humans and dairy products are the richest in calcium. On the contrary, a diet that includes fatty fish, beef liver and egg yolk provides only about 10% of vitamin D demand. Most vitamin D comes from skin synthesis.
Chung M, Balk EM, Brendel M, Ip S, Lau J, Lee J, Lichtenstein A, Patel K, Raman G, Tatsioni A, Terasawa T, Trikalinos TA. Vitamin D and calcium: a systematic review of health outcomes. Evid Rep Technol Assess (Full Rep). 2009; 183: 1–420.
Holick MF. Vitamin D status: measurement, interpretation, and clinical application. Ann Epidemiol 2009; 19: 73–78.
Bikle D. Nonclassic actions of vitamin D. J Clin Endocrinol Metab. 2009; 94: 26–34.
Grundmann M, Versen-Höynck F. Vitamin D – roles in women’s reproductive health? Reproductive Biology and Endocrinology 2011; 9: 146.
Evans KN, Bulmer JN, Kilby MD, Hewison M. Vitamin D and placentaldecidual function. J Soc Gynecol Investig. 2004; 11: 263–271.
Kovacs CS, Kronenberg HM. Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactation. Endocr Rev. 1997; 18: 832–872.
Kho AT, Bhattacharya S, Tantisira KG, et al. Transcriptomic analysis of human lung development. Am J Respir Crit Care Med. 2010; 181: 54–63.
Barker DJ, Eriksson JG, Forsen T, Osmond C. Fetal origins of adult disease: strength of effects and biological basis. Int J Epidemiol. 2002; 31: 1235–1239.
Pawley N, Bishop NJ. Prenatal and infant predictors of bone health: the influence of vitamin D Am J Clin Nutr. 2004; 80(Suppl.): 1748–1751.
Płudowski P, Karczmarewicz E, Bayer M, et al. Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe – recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency. Endokrynol Pol. 2013; 64: 319–327.
Charzewska J. Weker H. Polish national study on calcium and vitamin D contents in the diets of children aged 4 years. Pediatria Współczesna Gastroenterologia, Hepatologia i Żywienie Dziecka. 2006; 8: 107–109.
Szponar L, Wysocka B, Kierzkowska E. Calcium in the diet of selected groups of people. Pol Tyg Lek. 1991; 46: 575–578.
Wyka J, Biernat J. The comparison of food patterns of the elder people in 1990 and 2006. Rocz Panstw Zakl Hig. 2009; 60: 159–162.
Ilow R, Regulska-Ilow B, Różańska D, et al. Evaluation of mineral and vitamin intake in the diet of a sample of Polish population – baseline assessment from the prospective cohort ‘PONS’ study. Ann Agric Environ Med. 2011; 18: 235–240.
Skowrońska-Jóźwiak E, Jaworski M, Grzywa A, et al. Influence of calcium intake on bone mineral density and fractures incidence in the treatment-naive women from Lodz urban area – part of EPOLOS study. Ann Agric Environ Med. 2014, 21: 201–204.
Boylan S, Welch A, Pikhart H, et al. Dietary habits in three Central and Eastern European countries: the HAPIEE study. BMC Public Health. 2009; 9: 439.
Włodarek D, Głąbska D, Kołota A, et al. Calcium intake and osteoporosis: the influence of calcium intake from dairy products on hip bone mineral density and fracture incidence – a population-based study in women over 55 years of age. Public Health Nutr. 2012; 10: 1–7.
Bruyere O, De Cock C, Mottet C, et al. Low dietary calcium in European postmenopausal osteoporotic women. Public Health Nutr. 2009; 12: 111–114.
Ma J, Johns RA, Stafford RS. Americans are not meeting current calcium recommendations. Am J Clin Nutr. 2007; 85: 1361–1366.
Bojar I, Owoc A, Humeniuk E, Wierzba W, Fronczak A. Inappropriate consumption of vitamins and minerals by pregnant women in Poland. Ann Agric Environ Med. 2012; 19: 263–266.
Skowrońska-Jóźwiak E, Adamczewski Z, Tyszkiewicz A, et al. Assessment of adequacy of vitamin D supplementation during pregnancy. Ann Agric Environ Med. 2014; 21: 198–200.
Bolland MJ, Avenell A, Baron JA, et al. Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ. 2010; 341: 3691.
Jackson RD, LaCroix AZ, Gass M, et al. Women’s Health Initiative Investigators. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med. 2006, 16: 669–683.
American Society for Bone and Mineral Research (ASBMR) statement “Vitamin D and Calcium Supplementation to Prevent Fractures in Adults” www.asbmr.org/statements (access: 2014.03.31).
Zemel MB. Role of dietary calcium and dairy products in modulating adiposity. Lipids. 2003; 38: 139–146.
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