Alcohol-related Developmental Origin of Adult Health – population studies in Poland among mothers and newborns (2010-2012)
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Department of Health Promotion, Food and Nutrition, Institute of Rural Health, Lublin, Poland
Independent Laboratory of Molecular Biology, Institute of Rural Health, Lublin, Poland
Department of Public Health, University of Information Technology and Management, Rzeszow, Poland
Maria Curie-Skłodowska University, Lublin, Poland
Department of Biopharmacy, Medical University, Łódź, Poland
Department of Functional Research, Institute of Rural Health, Lublin, Poland
Ann Agric Environ Med. 2012;19(3):365-377
Alcohol related harm is a global problem for public health where frequent consumption of large amounts of alcohol constitutes a serious health risk, particularly to vulnerable groups such as adolescents, pregnant women and newborns. The epidemiological study on health-lifestyle behaviour, especially alcohol consumption, was performed on a randomised group of post-partum women’s health behaviour during pregnancy, covering drinking habits, was undertaken in 2010, 2011 and 2012, (n=8,237) according to the PRAMS model including effects on the foetus and newborn; women being selected from obstetric and gynaecological wards. In this Polish study, only 14% of women did not consume alcohol before becoming pregnant while 15% of women drank alcohol throughout the entire period of pregnancy. In addition, awareness of the harmful effects of alcohol consumed, especially of small amounts, before and during pregnancy is low among Polish women. It is also alarming that more than 55% of physicians who provide care for pregnant women do not discuss with them the harmful effect of alcohol on the organism of the mother and foetus, whereas over 2% of doctors even recommend the consumption of alcohol in pregnancy. With reference to the Barker’s Foetal Origin of Diseases Hypothesis, the authors suggest such alcohol drinking behaviour of women during their reproductive ages and while pregnant may exert negative health effects on offspring, mainly in the form of susceptibility to contracting chronic diseases. Such findings pose a risk to future generations in Poland and require remedial/educational action targeted on health care professionals and public like.
Jones KL, Smith DW, Ulleland CN, Streissguth AP. Pattern of malformation in offspring of chronic alcoholic mothers. Lancet 1973; 301(7815): 1267-1271.
Bertrand J, Floyd RL, Weber MK, O’Connor M, Riley EP, Johnson KA et al. Fetal Alcohol Syndrome: Guidelines for Referral and Diagnosis Centers for Disease Control and Prevention. 2004 Atlanta, GA NTFFAS/E.
Barry KL, Caetano R, Chang G, DeJoseph MC, Miller LA, O’Connor MJ et al. National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect. Reducing alcohol-exposed pregnancies: A report of the National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect. 2009, Atlanta, GA: Centers for Disease Control and Prevention.
Resnicoff M, Rubini M, Baserga R, Rubin R. Ethanol inhibits insulinlike growth factor-1-mediated signalling and proliferation of C6 rat glioblastoma cells. Lab Invest. 1994; 71: 657-662.
Goodlett CR, Horn KH. Mechanisms of alcohol-induced damage to the developing nervous system. Alcohol Res Health. 2001; 25: 175-184.
Haycock PC. Fetal Alcohol Spectrum Disorders: The Epigenetic Perspective. Biol Reprod. 2009; 81(4): 607-17.
Wozniak DF, Hartman RE, Boyle MP, Vogt SK, Brooks AR, Tenkova T et al. Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults. Neurobiol Dis. 2004; 17: 403-414.
Warren KR, Li TK. Genetic polymorphisms: impact on the risk of fetal alcohol spectrum disorders. Birth Defects Res A Clin Mol Teratol. 2005; 73: 195-203.
Skrzypczak J, Kwinecka-Dmitriew B, Zakrzewska M, Latos-Bieleńska A. Do chromosomal abnormalities reappear in subsequent pregnancies and how often? Ginekol Pol. 2010; 81(09): 681-686.
Larkby C, Day N. The effects on prenatal alcohol exposure. Alcohol Health Res. World, 1997; 21: 192-198.
Streissguth AP. Fetal Alcohol Syndrome: Early and long-term consequences. In: Problems with Drug Dependence: Proceedings of the 53rd Annual Scientific Meeting (NIDA Research Monograph No: 119) (Eds.) L Harris, Rockville MD, U.S. Department of Health and Human Services, 1991.
Jones KL, Smith DW. Recognition of Fetal Alcohol Syndrome in early infancy. Lancet. 1973; 302(7836): 999-1001.
Schenker S, Becker HC, Randall CL, Henderson GI. Fetal Alcohol Syndrome; Current status and pathogenesis. Alc Clin Exp Res. 1990, 14: 635-647.
Kwinecka-Dmitriew B, Zakrzewska M, Latos-Bieleńska A, Skrzypczak J. Frequency of chromosomal aberrations in material from abortions. Ginekol Pol. 2010; 81(12): 896-901.
Sandor GCS, Smith DF, MacLeod PM. Cardiac malformations in the Fetal Alcohol Syndrome. J Pediatr. 1981; 98(5): 771-773.
Baś-Budecka E, Perenc M, Sieroszewski P. The role of fetal nuchal translucency (NT) and ductus venosus blood flow (DV) in the detection of congenital heart defects.Ginekol Pol. 2010; 81(04): 272-276.
Pieroq S, Chandauasu O, Wexler I. Withdrawal symptoms in infants with the Fetal Alcohol Syndrome. J Pediatr. 1977; 90(4): 630.
Streissguth AP. Psychologic handicaps in children with Fetal Alcohol Syndrome. Ann N.Y. Acad Sci, 1976; 273: 140.
Abel EL, Sokol RJ. Incidence of Fetal Alcohol Syndrome and economic impact of FAS-related anomalities. Drug Alcohol Depend. 1987; 19: 51-70.
Jacobson JL, Jacobson SW. Effects of prenatal alcohol exposure on child development. Alcohol Health Res. World, 2002; 26: 282-286.
Lewis DD. Alcohol & pregnancy outcome. Midwives Chronicle & Nursing Notes, 1983; 420-423.
Stratton KR, Howe C, Battaglia F. (ed.). Fetal alcohol syndrome: Diagnosis, epidemiology, prevention, and treatment. 1996. Washington, DC: National Academy Press.
Kobor MS, Weinberg J. Focus on: Epigenetics and Fetal Alcohol Spectrum Disorders Alcohol Research & Health, Volume 34, Issue Number 1. (access: 2011.12.19).
Floyd RL, Denny C, Weber MK. Encyclopedia on Early Childhood Development 2011 CEECD/SKC-ECD (Published online August 2nd, 2011).
Manning MA, Hoyme EH. Fetal alcohol spectrum disorders: A practical clinical approach to diagnosis. Neurosci Biobehav Rev. 2007;31(2): 230-8.
Larkby CA, Goldschmidt L, Hanusa BH, Day NL.Prenatal alcohol exposure is associated with conduct disorder in adolescence: findings from a birth cohort. J Am Acad Child Adolesc Psychiatry. 2011 Mar; 50(3): 262-71.
Goodlett CR, Horn KH, Zhou FC. Alcohol teratogenesis: Mechanisms of damage and strategies for intervention. Exp Biol Med (Maywood). 2005; 230(6): 394-406.
Streissguth AP, Sampson PD, Olson HC, Bookstein FL, Barr HM, Scott M et al. Maternal drinking during pregnancy: attention and short-term memory in 14-year old offspring, a longitudinal prospective study. Alcohol Clin Exp Res. 1994; 18(1): 202-218.
Burden MJ, Jacobson SW, Sokol RJ, Jacobson JL. Effects of prenatal alcohol exposure on attention and working memory at 7.5 years of age. Alcohol Clin Exp Res. 2005; 29(3): 443-452.
Kelly Y, Sacker A, Gray R, Kelly J, Wolke D, Quigley MA. Light drinking in pregnancy, a risk for behavioural problems and cognitive deficits at 3 years of age? Int J Epidemiol. 2009; 38(1): 129-140.
Przewoźniak K, Łobaszewski J, Wojtyła A, Bylina J, Mańczuk M, Zatoński WA. Alcohol drinking patterns and habits among a sample of PONS study subjects: preliminary assessment. Ann Agric Environ Med. 2011; 18(2): 221-228.
Green ML, Singh AV, Zhang Y, Nemeth KA, Sulik KK, Knudsen TB. Reprogramming of genetic networks during initiation of the fetal alcohol syndrome. Developmental Dynamics 2007; 236: 613-631.
Warren KR, Li TK. Genetic polymorphisms: Impact on the risk of fetal alcohol spectrum disorders. Birth Defects Res A Clin Mol Teratol. 2005; 73(4): 195-203.
Jacobson SW, Carr LG, Croxford J, Sokol RJ, Li TK, Jacobson JL. Protective effects of the alcohol dehydrogenase-ADH1B allele in children exposed to alcohol during pregnancy. J Pediatr. 2006; 148: 30-37.
McCarver DG, Thomasson HR, Martier SS, Sokol RJ, Li T. Alcohol dehydrogenase-2*3 allele protects against alcohol-related birth defects among African Americans. J Pharmacol Exp Ther. 1997; 283(3): 1095-101.
Stoler JM, Ryan LM, Holmes LB. Alcohol dehydrogenase 2 genotypes, maternal alcohol use, and infant outcome. J Pediatr. 2002; 141: 780-785.
Viljoen DL, Carr LG, Foroud TM. Brooke L, Ramsay M, Li TK. Alcohol dehydrogenase-2*2 allele is associated with decreased prevalence of fetal alcohol syndrome in the mixed-ancestry population of the Western Cape Province, South Africa. Alcohol Clin Exp Res. 2001; 25(12): 1719-22.
Soltes BA, Anderson R, Radwanska E. Morphologic changes in offspring of female mice exposed to ethanol before conception. Am J Obstet Gynecol. 1996; 175: 1158-1162.
IARC. Acetaldehyde. In: IARC monographs on the evaluation of the carcinogenic risk tohumans. Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide. Lyon: International Agency for Research on Cancer, 1999; 71: 319-335.
Lombard Z, Tiffin N, Hofmann O, Bajic VB, Hide W, Ramsay M. Computational selection and prioritization of candidate genes for fetal alcohol syndrome. BMC Genomics. 2007; 8: 389.
Ballard MS, Sun M, Ko J. Vitamin A, folate, and choline as a possible preventive intervention to fetal alcohol syndrome. Med Hypotheses. 2012; 78(4): 489-93.
Abel E. Paternal contribution to fetal alcohol syndrome. Addict Biol. 2004; 9(2): 127-33.
Reynolds JN, Weinberg J, Clarren S, Beaulieu C, Rasmussen C, Kobor M et al. Fetal alcohol spectrum disorders: gene-environment interactions, predictive biomarkers, and the relationship between structural alterations in the brain and functional outcomes. Semin Pediatr Neurol. 2011; 18(1): 49-55.
Barak AJ, Beckenhauer HC, Tuma DJ, Badakhsh S. Effects of prolonged ethanol feeding on methionine metabolism in rat liver. Biochem Cell Biol. 1987; 65(3): 230-3.
Finkelstein JD, Cello JP, Kyle WE. Ethanol-induced changes in methionine metabolism in rat liver. Biochem Biophys Res Commun. 1974; 61(2): 525-31.
Halsted CH, Villanueva J, Chandler CJ, Stabler SP, Allen RH, Muskhelishvili L et al. Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation. Hepatology. 1996; 23: 497-505.
Barak AJ, Beckenhauer HC, Junnila M, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethionine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res. 1993; 17(3): 552-5.
Lieber CS. Biochemical and molecular basis of alcohol-induced injury to liver and other tissues. N Engl J Med. 1988; 319(25): 1639-50.
Lu SC, Huang ZZ, Yang H, Mato JM, Avila MA, Tsukamoto H. Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liver. Am J Physiol Gastrointest Liver Physiol. 2000; 279(1): G178-85.
Mato JM, Lu SC. Role of S-adenosyl-L-methionine in liver health and injury. Hepatology. 2007; 45: 1306-1312.
Shukla SD, Velazquez J, French SW. Lu SC, Ticku MK, Zakhari S. Emerging role of epigenetics in the actions of alcohol. Alcohol Clin Exp Res. 2008; 32(9): 1525-34.
Kim JS, Shukla SD. Acute in vivo effect of ethanol (binge drinking) on histone H3 modifications in rat tissues. Alcohol Alcohol. 2006; 41(2): 126-32.
Halsted CH, Villanueva JA, Devlin AM, Chandler CJ. Metabolic interactions of alcohol and folate. J Nutr. 2002; 132(8 Suppl): 2367S-2372S.
Naughton CA, Chandler CJ, Duplantier RB, Halsted CH. Folate absorption in alcoholic pigs: In vitro hydrolysis and transport at the intestinal brush border membrane. Am J Clin Nutr. 1989; 50(6): 1436-41.
Hillemacher T, Frieling H, Hartl T, Wilhelm J, Kornhuber J, Bleich S. Promoter specific methylation of the dopamine transporter gene is altered in alcohol dependence and associated with craving. J Psychiatr Res. 2009; 43(4): 388-92.
Bönsch D, Lenz B, Fiszer R, Frieling H, Kornhuber J, Bleich S. Lowered DNA methyltransferase (DNMT-3b) mRNA expression is associated with genomic DNA hypermethylation in patients with chronic alcoholism. J Neural Transm. 2006; 113(9): 1299-304.
Ramsay M. Genetic and epigenetic insights into fetal alcohol spectrum disorders. Med. 2010; 28; 2(4): 27.
Anderson RA, JR. Furby JE, Oswald C, Zaneveld LJ. Teratological evaluation of mouse fetuses after paternal alcohol ingestion. Neurobehav Toxicol Teratol. 1981; 3(2): 117-20.
Redei EE. Paternal genetic contribution influences fetal vulnerability to maternal alcohol consumption in a rat model of fetal alcohol spectrum disorder, 2010; PLoS One 5:e10058.
Piotrowski K, Constantinou M, Patalan J, Waloszczyk P, Celewicz Z, Kałużewski B et al. Prenatal diagnosis of rare fetal anomalies – a case report. Ginekol Pol. 2011; 82(07): 541-545.
Bielawski DM, Zaher FM, Svinarich DM, Abel EL. Paternal alcohol exposure affects sperm cytosine methyltransferase messenger RNA levels. Alcohol Clin Exp Res. 2002; 26: 347-351.
Ouko LA, Shantikumar K, Knezovich J, Haycock P, Schnugh DJ, Ramsay M. Effect of alcohol consumption on CpG methylation in the differentially methylated regions of H19 and IG-DMR in male gametes: Implications for fetal alcohol spectrum disorders Alcohol Clin Exp Res. 2009; 33: 1615-1627.
Livy DJ, Maier SE, West JR. Long-term alcohol exposure prior to conception results in lower fetal body weights. Birth Defects Res B Dev Reprod Toxicol. 2004; 71(3): 135-41.
Kaminen-Ahola N, Ahola A, Maga M, Mallitt KA, Fahey P, Cox TC et al. Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model. 2010; PLoS Genet. 6:e1000811.
Bucholc M, Oleszczuk J, Leszczyńska-Gorzelak B. Selected determinants of body mass in premature infants. Ginekol Pol. 2010; 81(01): 37-40.
Waterland RA, Dolinoy DC, Lin J-R, Smith CA, Shi X, Tahiliani KG. Maternal methyl supplements increase offspring DNA methylation at Axin fused. Genesis. 2006; 44(9): 401-6.
Padmanabhan R, Hameed MS. Effects of acute doses of ethanol administered at pre-implantation stages on fetal development in the mouse. Drug Alcohol Depend. 1988; 22(1-2): 91-100.
Haycock PC, Ramsay M. Exposure of mouse embryos to ethanol during preimplantation development: Effect on DNA methylation in the h19 imprinting control region. Biol Reprod. 2009; 81: 618-627.
Garro AJ, McBeth DL, Lima V, Lieber CS. Ethanol consumption inhibits fetal DNA methylation in mice: Implications for the fetal alcohol syndrome. Alcohol Clin Exp Res. 1991; 15: 395-398.
Haley DW, Handmaker NS, Lowe J. Infant stress reactivity and prenatal alcohol exposure. Alcohol Clin Exp Res 2006; 30: 2055-2064.
Berman RF, Hannigan JH. Effects of prenatal alcohol exposure on the hippocampus: spatial behavior, electrophysiology, and neuroanatomy. Hippocampus. 2000; 10: 94 –110.
Hamilton DA, Kodituwakku P, Sutherland RJ, Savage DD. Children with Fetal Alcohol Syndrome are impaired at place learning but not cuednavigation in a virtual Morris water task. Behav Brain Res. 2003; 143: 85-94.
Colantoni A, Idilman R, De Maria N, La Oaglia N, Belmonte J, Wezeman F et al. Hepatic apoptosis and proliferation in male and female rats fed alcohol: role of cytokines. Alcohol Clin Exp Res. 2003; 27: 1184-1189.
Kesmodel U, Wisborg K, Olsen SF, Henriksen TB, Secher NJ. Moderate alcohol intake during pregnancy and the risk of stillbirth and death in the first year of life. Am J Epidemiol. 2002; 155: 305-312.
Chaudhuri JD. Alcohol and developing fetus: a review. Med Sci Monit. 2000; 6(5): 1031-1041.
Silva I, Quevedo Lde A, Silva RA, Oliveira SS, Pinheiro RT. Association between alcohol abuse during pregnancy and birth weight. Rev Saude Publica. 2011; 45(5): 864-9.
Scheuplein R, Charnley G, Dourson M. Differential sensitivity of children and adults to chemical toxicity. Regul Toxicol Pharmacol. 2002; 35: 429-447.
Hines N, McCarver D. Ontogeny of human drug-metabolizing enzymes: Phase I oxidative enzymes. J Pharmacol Exp Ther. 2002; 300: 355-360.
Fischer D, Solbach C, Kitz R, Ahr A, Veldman A. Acute ethanol intoxication during pregnancy and consecutive fetal cardiac arrest: a case report. J Perinat Med. 2003; 31: 343-344.
The Swedish National Institute of Public Health. Low dose alcohol exposure during pregnancy—does it harm? A systematic literature review. Stockholm: Stromberg; 2009.: 2011.02.19).
Hellemans KG, Verma P, Yoon E, Yu W, Weinberg J. Prenatal alcohol exposure increases vulnerability to stress and anxiety-like disorders in adulthood. Ann N Y Acad Sci. 2008; 1144: 154-75.
Testa M, Quigley BM, Eiden RD. The effects of prenatal alcohol exposure on infant mental development: a meta-analytical review. Alcohol. 2003; 38(4): 295-304.
Wojtyła A. Application of the hypothesis of Developmental Origin of Health and Diseases (DOHaD) in epidemiological studies of women at reproductive age and pregnant women in Poland.Ann Agric Environ Med. 2011; 18(2): 355-364.
Skinner MK, Guerrero-Bosagna C. Environmental signals and transgenera- tional epigenetics. Epigenomics. 2009; 1: 111-117.
Anway MD, Leathers C, Skinner MK. Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease. Endocrinology. 2006; 147: 5515-5523.
Wojtyła A, Kapka-Skrzypczak L, Biliński P, Paprzycki P. Physical activity among women at reproductive age and during pregnancy (Youth Behavioural Polish Survey – YBPS and Pregnancy-related Assessment Monitoring Survay – PrAMS) – epidemiological population studies in Poland during the period 2010-2011. Ann Agric Environ Med. 2011; 18(2): 365-374.
Perera F, Herbstman J. Prenatal environmental exposures, epigenetics, and disease. Reprod Toxicol. 2011; 31(3): 363-373.
Wojtyła A, Kapka-Skrzypczak L, Paprzycki P, Skrzypczak M, Biliński P. Epidemiological studies in Poland on effect of physical activity of pregnant women on the health of offspring and future generations – adaptation of the hypothesis Development Origin of Health and Diseases. Ann Agric Environ Med. 2012; 19(2): 315-326.
Burd L, Klug MG, Martsolf JT, Martsolf C, Deal E, Kerbashian J. A staged screening strategy for prenatal alcohol exposure and maternal risk stratification. J R Soc Promot Health. 2006; 126: 86-94.
World Health Organization. Global status report on alcohol and health. WHO 2011. (access: 2011.11.19).
O’Connor MJ, Whaley SE. Brief Intervention for Alcohol Use by Pregnant Women. Am J Public Health. 2007; 97: 252-258.
Anderson JE, Ebrahim S, Floyd L, Atrash H. Prevalence of Risk Factors for Adverse Pregnancy Outcomes During Pregnancy and the Preconception Period. Matern Child Health J. 2006; 10: 101-106.
Chang G, McNamara TK, Orav EJ, Wilkins-Haug L. Alcohol Use by Pregnant Women: Partner’s, Knowledge and Other Predictors. J Stud Alcohol Drugs. 2006; 67: 245-251.
O’Callaghan FV, O’Callaghan M, Najman JM, Williams GM, Bor W. Maternal alcohol consumption during pregnancy and physical outcomes up to 5 years of age: a longitudinal study. Early Hum Dev. 2003; 71: 137-148.
Malet L, de Chazeron I, Llorca PM, Lemery D. Alcohol Consumption During Pregnancy: An Urge to Increase Prevention and Screening. Eur J Epidemiol. 2006; 21: 787-788.
Walker MJ, Al-Sahab B, Islam F, Tamim H. The epidemiology of alcohol utilization during pregnancy: an analysis of the Canadian Maternity Experiences Survey (MES). BMC Pregnancy Childbirth. 2011; 11: 52.
Bonati M, Fellin G. Changes in smoking and drinking behaviour before and during pregnancy in Italian mothers: Implications for public health intervention. Int J Epidemiol. 1991; 20: 927-932.
Lee SH, Shin SJ, Won SD, Kim EJ, Oh DY. Alcohol Use during Pregnancy and Related Risk Factors in Korea. Psychiatry Investig. 2010; 7(2): 86-92.
Kesmodel U, Kesmodel PS, Larsen A, Secher NJ. Use of alcohol and illicie drugs among pregnant Danish women, 1998. Scand J Public Health. 2003; 31(1): 5-11.
Mullally A, Cleary BJ, Barry J, Fahey TP, Murphy DJ. Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure-retrospective cohort study in an urban obstetric population in Ireland. BMC Pregnancy Childbirth. 2011; 11: 27.
Przewoźniak K, Łobaszewski J, Wojtyła A, Bylina J, Mańczuk M, Zatoński WA. Alcohol drinking patterns and habits among a sample of PONS study subjects: preliminary assessment Ann Agric Environ Med. 2011; 18(2): 221-228.
Zagozdzon P, Kolarzyk E, Marcinkowski JT. Quality of life and rural place of residence in Polish women population based study Ann Agric Environ Med. 2011; 18(2): 429-43.
Henderson J, Kesmodel U, Gray R. Systematic review of the fetal effects of prenatal binge-drinking. J Epidemiol Community Health. 2007, 61: 1069-1073.
Albertsen K, Andersen AN, Olsen J, Gronbaek M. Alcohol Consumption during Pregnancy and the Risk of Preterm Delivery. Am J Epidemiol 2004, 159: 155-161.
Onischenko G. Ob usilcnii nadzora za proizvodstvom i oborotom alkogol4noj produk, icj [Strengthening the supervision over the production and sale of alcohol products]. Resolution no. 7, Moscow. 2007. 29 April 2011. content? groupId=10156&articleId=82037&version=1.0 (access: 2010.10.11).
Chambers CD, Kavteladze L, Joutchenko L, Bakhireva LN, Jones KL. Alcohol consumption patterns among pregnant women in the Moscow region of the Russian Federation. Alcohol. 2006; 38: 133-137.
Kristjanson AF, Wilsnack SC, Zvartau E, Tsoy M, Novikov B. Alcohol use in pregnant and non-pregnant Russian women. Alcohol Clin Exp Res. 2007; 31: 299-307.
Chambers CD, Hughes S, Meltzer SB, Wahlgren D, Kassem N, Larson S, et al.Alcohol consumption among low-income pregnant Latinas. Alcohol Clin Exp Res. 2005 Nov; 29(11): 2022-8.
Balachova T, Bonner B, Chaffin M, Bard D, Isurina G, Tsvetkova L et al. Women’s alcohol consumption and risk for alcohol-exposed pregnancies in Russia, 2011, Addiction. 107: 109-117.
Finer LB, Henshaw SK. Disparities in rates of unintended pregnancy in the United States, 1994 and 2001. Perspect Sex Reprod Health. 2006; 38(2): 90-96.
Floyd RL, Ebrahim SH, Boyle CA. Observations from the CDC. Preventing alcohol-exposed pregnancies among women of childbearing age: the necessity of a preconceptional approach. J Womens Health Gend Based Med. 1999; 8: 733-736.
Floyd RL, Decoufle P, Hungerford DW. Alcohol use prior to pregnancy recognition. Am J Prev Med. 1999; 17(2): 101-107.
Tough S, Tofflemire K, Clarke M, Newburn-Cook C. Do women change their drinking behaviors while trying to conceive? An opportunity for preconception counseling. Clin Med Res. 2006; 4(2): 97-105.
Centers for Disease Control and Prevention. Alcohol consumption among women who are pregnant or who might become pregnant—United States, 2002. MMWR Morb Mortal Wkly Rep. 2004; 53(50): 1178-1181.
Olson HC, Ohlemiller MM, O‘Connor MJ, Brown CW, Morris CA, Damus K. National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect. A call to action: Advancing essential services and research on fetal alcohol spectrum disorders –A report of the National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect. Atlanta, GA: Centers for Disease Control and Prevention; 2009.
Weber MK, Floyd RL, Riley EP, Snider DE. National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect: Defining the national agenda for fetal alcohol syndrome and other prenatal alcohol-related effects. MMWR Recomm Rep. 2002; 51 (RR-14): 9-12.
United States Department of Health and Human Services. Advisory on alcohol use in pregnancy. 2005 (access: 2011.12.19).
Bertrand J. Interventions for Children with Fetal Alcohol Spectrum Disorders Research Consortium.Interventions for children with fetal alcohol spectrum disorders (FASDs): overview of findings for five innovative research projects. Res Dev Disabil. 2009; 30(5): 986-1006.
Centers for Disease Control and Prevention. Fetal alcohol syndrome – Alaska, Arizona, Colorado, and New York, 1995-1997. MMWR. 2002; 51: 433-435.
Centers for Disease Control and Prevention. Surveillance for fetal alcohol syndrome using multiple sources – Atlanta, Georgia, 1981-1989. MMWR. 1997; 46: 1118-1120.
May PA, Gossage JP. Estimating the prevalence of fetal alcohol syndrome: a summary. Alcohol Res Health. 2001; 25(3): 159-167.
Sokol RJ, Delaney-Black V, Nordstrom B. Fetal alcohol spectrum disorder. JAMA. 2003; 290(22): 2996-2999.
Alcohol Beverage Labeling Act of 1988, Pub.L. No. 100-690 S27(1988).
Hankin JR, Firestone IJ, Sloan JJ, Ager JW, Sokol RJ, Martier SS. Heeding the alcoholic beverage warning label during pregnancy: Multiparae versus nulliparae. J Stud Alcohol. 1996; 57(2): 171-177.
Hankin JR, Sloan JJ, Firestone IJ, Ager JW, Sokol RJ, Martier SS. A time series analysis of the impact of the alcohol warning label on antenatal drinking. Alcohol Clin Exp Res. 1993; 17(2): 284-289.
Truman BI, Smith-Akin CK, Hinman AR, Gebbie KM, Brownson R, Novick LF, et al. Developing the Guide to Community Preventive Services-Overview and rationale. The Task Force on Community Preventive Services. Am J Prev Med. 2000; 18(1 Suppl): 18-26.
Stratton KR, Howe C, Battaglia F, editors. Fetal alcohol syndrome: Diagnosis, epidemiology, prevention, and treatment. Washington, DC: National Academy Press; 1996.
Glik D, Halpert-Schilt E, Zhang W. Narrowcasting risks of drinking during pregnancy among African American and Latina adolescent girls. Health Promot Pract. 2001; 2(3): 222-232.
Kaskutas LA, Graves K. Relationship between cumulative exposure to health messages and awareness and behavior-related drinking during pregnancy. Am J Health Promot. 1994; 9(2): 115-124.
Prugh T. Point-of-purchase health warning notices. Alcohol Health Res World. 1986; 10(4): 36.
Sokol RJ, Martier SS, Ager JW. The T-ACE questionnaire: practical prenatal detection of risk-drinking. Am J Obstet Gynecol. 1989; 160: 863-868.
Chang G, Wilkins-Haug L, Berman S, Goetz M, Behr S. Alcohol use and pregnancy: improving identification. Obstet Gynecol. 1998; 91: 892-898.
Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the Alcohol Use Disorders Identification Test (AUDIT). Addiction. 1993; 88(6): 791-804.
Knight JR, Sherritt L, Harris SK, Gates EA, Chang G. Validity of brief alcohol screening tests among adolescents: a comparison of the AUDIT, CAGE, POSIT and CRAFFT. Alcohol Clin Exp Res 2003; 27: 67-73.
Bradley KA, Boyd-Wickizer J, Powell SH, Burman ML. Alkohol screening questionnaires in women: a critical review. JAMA. 1998; 280: 166-171.
Chang G, Goetz MA, Wilkins-Haug L, Berman S. Identifying prenatal alcohol use: screening instruments versus clinical predictors. 1999; Am J Addict. 8: 87-93.
Dawson DA, Grant BF, Stinson FS, Zhou Y. Effectiveness of the derived Alcohol Use Disorders Identification Test (AUDIT-C) in screening for alcohol use disorders and risk drinking in the US general population. Alcohol Clin Exp Res. 2005; 29(5): 844-854.
Russell M, Martier SS, Sokol RJ, Mudar P, Bottoms S, Jacobson S et al. Screening for pregnancy risk-drinking. Alcohol Clin Exp Res. 1994; 18(5): 1156-1161.
Russell M. New assessment tools for drinking during pregnancy, T-ACE, TWEAK, and others. Alcohol Health Res World. 1994; 18: 55-61.
Russell M, Martier SS, Sokol RJ, Mudar P, Jacobson S, Jacobson J. Detecting risk drinking during pregnancy: A comparison of four screening questionnaires. Am J Public Health. 1996; 86(10): 1435-1439.
U.S. Surgeon General Releases Advisory on Alcohol Use in Pregnancy. News Release, 2005. U.S. Departament of Health & Human Services. (access: 2011.12.19).
Drinking and Reproductive Health. A Fetal Alcohol Spectrum Disorders Prevention Tool Kit. Washington (DC): The American College of Obstetricians and Gynecologists; 2006.
Centers for Disease Control and Prevention. Alcohol use among pregnant and nonpregnant women of childbearing age-United States, 1991-2005. MMWR Morb Mortal Wkly Rep 2009; 58: 529-532.
Diekman ST, Floyd RL, De´coufle´ P, Schulkin J, Ebrahim SH, Sokol RJ. A survey of obstetrician-gynecologists on their patients’ alcohol use during pregnancy. Obstet Gynecol. 2000; 95: 756-763.
Adams MM, Shulman HB, Bruce C, Hogue C, Brogan D. The Pregnancy Risk Assessment Monitoring System: design, questionnaire, data collection, and response rates. PRAMS Working Group. Paediatr Perinat Epidemiol. 1991; 5: 333-346.
Results from the 2008 National Survey on Drug Use and Health: National findings. NSDUH Series H-36, HHS Publications No. SMA 09-4434. Rockville (MD): Office of Applied Studies; 2008.
American College of Obstetricians and Gynecologists. ACOG Committee Opinion No. 422. At-risk drinking and illicit drug use: ethical issues in obstetric and gynecologic practice. Obstet Gynecol. 2008; 112: 1449-1460.
Cheng D, Kettinger L. Uduhiri K, Hurt L. Alcohol Consumption During Pregnancy. Prevalence and Provider Assessment. Obstet. 2011; 117: 212-217.
Fiellin DA, Reid MC, O’Connor PG. Screening for alcohol problems in primary care: A systematic review. Arch Intern Med. 2000; 160(13): 1977-1989.
Jacobson SW, Chiodo LM, Sokol RJ, Jacobson JL. Validity of maternal report of prenatal alcohol, cocaine, and smoking in relation to neurobehavioral outcome. Pediatrics. 2002; 109(5): 815-825.
American College of Obstetricians and Gynecologists. ACOG Committee Opinion. Number 294, May 2004. At-risk drinking and illicit drug use: Ethical issues in obstetric and gynecologic practice. Obstet Gynecol. 2004; 103(5 Pt 1): 1021-1031.
Floyd RL, O’Connor MJ, Bertrand J, Sokol RJ. Reducing adverse outcomes from prenatal alcohol exposure: A clinical plan of action. Alcohol Clin Exp Res. 2006; 30(8): 1271-1275.
Hingson R, Heeren T, Winter M, Wechsler H. Magnitude of alcohol-related mortality and morbidity among U.S. college students ages 18-24: Changes from 1998 to 2001. Annu Rev Public Health. 2005; 26: 259-279.
Task Force of the National Advisory Council on Alcohol Abuse and Alcoholism. A Call to Action: Changing the Culture of Drinking at U.S. Colleges. Rockville, MD: National Institute on Alcohol Abuse and Alcoholism; 2002. NIH Publication 02-5010.
Cooper ML, Peirce RS, Huselid RF. Substance use and sexual risk taking among black adolescents and white adolescents. Health Psychol. 1994; 13(3): 251-262.
Young AM, Morales M, McCabe SE, Boyd CJ, Título DH. Drinking like a guy: Frequent binge drinking among undergraduate women. Subst Use Misuse. 2005; 40(2): 241-267.
O’Malley PM, Johnston LD. Epidemiology of alcohol and other drug use among American college students. J Stud Alcohol Suppl. 2002; 14: 23-39.
Sochaczewska D, Czeszyńska M, Konefał H, Garanty-Bogacka B. Maternal active or passive smoking in relation to some neonatal morphological parameters and complications.Ginekol Pol. 2010; 81(09): 687-692.
Dimeff LA, Baer JS, Kivlahan DR, Marlatt GA. Brief alcohol screening and intervention for college students (BASICS). Subst Abus. 1999; 21(4): 283-285.
Baer JS, Kivlahan DR, Blume AW, McKnight P, Marlatt GA. Brief intervention for heavy-drinking college students: 4-year follow-up and natural history. Am J Public Health. 2001; 91(8): 1310-1316.
Cotton NS. The familial incidence of alcoholism: A review. J Stud Alcohol. 1979; 40(1): 89-116.
Emshoff JG, Price AW. Prevention and intervention strategies with children of alcoholics. Pediatrics. 1999; 103(5 Pt 2): 1112-1121.
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