CASE REPORT
Mucormycosis in a patient with acute myeloblastic leukemia following liver transplantation for Wilson’s disease
 
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Pomeranian Medical University, Szczecin, Poland
CORRESPONDING AUTHOR
Aleksandra Anna Łanocha   

Pomeranian Medical University in Szczecin, Poland
 
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ABSTRACT
A case is presented of mucormycosis in a patient with acute myeloblastic leukemia following liver transplantation for Wilson’s disease. A 58-year-old female was admitted to the Department of Haematology with deterioration of her general condition, loss of appetite, tiredness and difficulty with mental contact for a few days. Blood and urine cultures for bacteria and fungus, galactomannan antigen were negative. Whole body computed tomography demonstrated bilateral hilar lymphadenopathy with necrotic lesions: splenomegaly with a hypodensive lesion 13 × 20 × 19 mm and lower pulmonary infiltrates suggested fungal etiology. Magnetic resonance imaging of the brain showed thickened meninges. Finally, mucormycosis was diagnosed. Treatment with amphotericin B lipid complex was started, resulting in an partial improvement of the general condition and decreased level of inflammatory markers. However, the patient’s condition continued to deteriorate, with sepsis etiology Escherichia coli, and despite the intensive managements she eventually died.
ACKNOWLEDGEMENTS
The authors would like to thank Dr Ewa Gabrysz-Trybek for assistance with preparation of the Figures.
CONFLICT OF INTEREST
The authors declare no conflict of interest.
FUNDING
The research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
 
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