Influence of hyperosmotic conditions on basophil CD203c upregulation in patients with food-dependent exercise-induced anaphylaxis.
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Department of Internal Medicine and Allergology, Wroclaw Medical University, Wrocław, Poland
Department of Physiology, Wroclaw Medical University, Wrocław, Poland
Anna Wolanczyk-Medrala   

Prof. Wojciech Medrala, MD, Ph.D., Department of Internal Medicine and Allergology, Wroclaw Medical University, Traugutta 57/59, 50-417 Wroclaw, Poland.
Ann Agric Environ Med. 2009;16(2):301–304
Increased in vitro basophil activation in buffers of slightly elevated osmolarity in 2 cases of food-dependent exercise-induced anaphylaxis is presented. These data may suggest the importance of basophil activation degree in pathogenesis of this life threatening syndrome.
Aihara M, Miyazawa M, Osuna H, Tsubaki K, Ikebe T, Aihara Y, Ikezawa Z: Food-dependent exercise-induced anaphylaxis: influence of concurrent aspirin administration on skin testing and provocation. Br J Dermatol 2002, 146, 466-472.
Anderson SD, Daviskas E: The mechanism of exercise-induced asthma is… J Allergy Clin Immunol 2000, 106, 453-459.
Banks JR, Kagey-Sobotka A, Lichenstein LM, Eggleston PA: Spontaneous histamine release after exposure to hyperosmolar solutions. J Allergy Clin Immunol 1986, 78, 51-57.
Barg W, Wolanczyk-Medrala A, Obojski A, Wytrychowski K, Panaszek B, Medrala W: Food-dependent exercise-induced anaphylaxis: possible impact of increased basophil histamine releasability in hyperosmolar conditions. J Invest Allergol Clin Immunol 2008, 18, 312-315.
Boumiza R, Debard AL, Monneret G: The basophil activation test by flow cytometry: recent developments in clinical studies, standardization and emerging perspectives. Clin Mol Allergy 2005, 3, 9.
De Weck AL, Sanz ML, Gamboa PM, Aberer W, Bienvenu J, Blanca M, Demoly P, Ebo DG, Mayorga L, Monneret G, Sainte-Laudy J: Diagnostic tests based on human basophils: more potentials and perspectives than pitfalls. Int Arch Allergy Immunol 2008, 146, 177-189.
Dohi M, Suko M, Sugiyama H, Yamashita N, Tadokoro K, Juji F, Okudaira H, Sano Y, Ito K, Miyamoto T: Food-dependent, exercise-induced anaphylaxis: a study on 11 Japanese cases. J Allergy Clin Immunol 1991, 87, 34-40.
Eberlein-König B, Varga R, Mempel M, Darsow U, Behrendt H, Ring J: Comparison of basophil activation tests using CD63 or CD203c expression in patients with insect venom allergy. Allergy 2006, 61, 1084-1085.
Ebo DG, Sainte-Laudy J, Bridts CH, Mertens CH, Hagendorens MM, Schuerwegh AJ, De Clerck LS, Stevens WJ: Flow-assisted allergy diagnosis: current application and future perspectives. Allergy 2006, 61, 1028-1039.
Eggleston PA, Kagey-Sobotka A, Proud D, Adkinson NF Jr, Lichtenstein LM: Dissociation of the release of histamine and arachidonic acid metabolism from osmotically activated basophils and human mast lung cells. Am Rev Respir Dis 1990, 141, 960-964.
Eggleston PA, Kagey-Sobotka A, Schleimer RP, Fink JN: Interaction between hyperosmolar and IgE-mediated histamine release from basophils and mast cells. Am Rev Respir Dis 1984, 130, 86-91.
Fukutomi O, Kondo N, Agata H, Shinoda S, Shinbara M, Orii T: Abnormal responses of the autonomic nervous system in food-dependent exercise-induced anaphylaxis. Ann Allergy 1992, 68, 438-445.
Fujii H, Kambe N, Fujisawa A, Kohno K, Morita E, Miyachi Y: Food-dependent exercise-induced anaphylaxis induced by low dose aspirin therapy. Allergol Int 2008, 57, 97-98.
Harada S, Horikawa T, Ashida M, Kamo T, Nishioka E, Ichihashi M: Aspirin enhances the induction of type I allergic symptoms when combined with food and exercise in patients with food-dependent exerciseinduced anaphylaxis. Br J Dermatol 2001, 145, 336-339.
Kahlert H, Cromwell O, Fiebig H: Measurement of basophil activating capacity of grass pollen allergens, allergoids and hypoallergenic recombinant derivatives by flow cytometry using anti-CD 203c. Clin Exp Allergy 2003, 33, 1266-1272.
Katsunuma T, Iikura Y, Akasawa A, Iwasaki A, Hashimoto K, Akimoto K: Wheat-dependent exercise-induced anaphylaxis: inhibition by sodium bicarbonate. Ann Allergy 1992, 68, 184-188.
Khamnei S, Alipour MR, Ahmadiasl N: The combined effects of exercise and post dehydration water drinking on plasma argenine vasopressin, plasma osmolality and body temperature in healthy males. Int J Endocrinol Metab 2005, 2, 80-86.
Matsuo H, Morimoto K, Akaki T, Kaneko S, Kusatake K, Kuroda T, Niihara H, Hide M, Morita E: Exercise and aspirin increase levels of circulating gliadin eptides in patients with wheat-dependent exercise-induced anaphylaxis. Clin Exp Allergy 2005, 35, 461-466.
Maulitz RM, Pratt DS, Schocket AL: Exercise-induced anaphylactic reaction to shellfish. J Allergy Clin Immunol 1979, 63, 433-434.
Nielsen BW, Bjerke T, Damsgaard TM, Herlin T, Thestrup-Pedersen K, Schiotz PO: Hyperosmolarity selectively enhances IgE-receptormediated histamine release from human basophils. Agents Actions 1992, 35, 170-178.
Oyefara BI, Bahna SL: Delayed food-dependent, exercise-induced anaphylaxis. Allergy Asthma Proc 2007, 28, 64-66.
Pals KL, Chang RT, Ryan AJ, Gisolfi CV: Effect of running intensity on intestinal permeability. J Appl Physiol 1997, 82, 571-576.
Romano A, Di Fonso M, Giuffreda F, Papa G, Artesani MC, Viola M, Venuti A, Palmieri V, Zeppilli P: Food-dependent exercise-induced anaphylaxis: clinical and laboratory findings in 54 subjects. Int Arch Allergy Immunol 2001, 125, 264-272.
Sanz ML, Sanchez G, Gamboa PM, Vila L, Uasuf C, Chazot M, Dieguez I, De Weck AL: Allergen-induced basophil activation: CD63 cell expression detected by flow cytometry in patients allergic to Dermatophagoides pteronyssinus and Lolium perenne. Clin Exp Allergy 2001, 31, 1007-1013.
Smetanka RD, Lambert GP, Murray R, Eddy D, Horn M, Gisolfi CV: Intestinal permeability in runners in the 1996 Chicago marathon. Int J Sport Nutr 1999, 9, 426-433.
Stellato C, de Crescenzo G, Patella V, Mastronardi P, Mazzarella B, Marone B: Human basophil/mast cells releasibility XI. Heterogeneity of the effects of contrast media on mediator release. J Allergy Clin Immunol 1996, 97, 838-850.
Volcheck GW, Li JT: Exercise-induced urticaria and anaphylaxis. Mayo Clin Proc 1997, 72, 140-147.