RESEARCH PAPER
Identification of infectious microbiota from oral cavity environment of various population group patients as a preventive approach to human health risk factors
| 1 | Clinic of Cranio-Maxillo-Facial and Oral Surgery and Implantology, Medical University of Warsaw, Warsaw, Poland |
| 2 | Department of Orthodontics, Medical University of Warsaw, Warsaw, Poland |
| 3 | Department of Pharmaceutical Microbiology, Medical University of Warsaw, Warsaw, Poland, |
| 4 | Department of Medical Biology, Medical University of Warsaw, Warsaw, Poland |
| 5 | Department of Disaster Medicine, Medical University of Warsaw, Poland |
CORRESPONDING AUTHOR
Paweł J. Zawadzki
Clinic of Cranio-Maxillo-Facial and Oral Surgery and Implantology, Medical University of Warsaw, Warsaw, Poland
Clinic of Cranio-Maxillo-Facial and Oral Surgery and Implantology, Medical University of Warsaw, Warsaw, Poland
Ann Agric Environ Med. 2016;23(4):566–569
KEYWORDS
ABSTRACT
Introduction and objective:
This study presents the results of comparative investigations aimed to determine microbiota that can occur in the oral environment in different human populations. The objective of the research was to identify pathogenic oral microbiota, the potential cause of health complications in patients of different population groups.
Material and Methods:
The study included 95 patients requiring dental or surgical treatment; their oral cavity environment microbiota as risk factors of local and general infections were assessed.
Results:
In clinical assessment, differences occurred in oral cavity conditions between patients with malformations of the masticatory system, kidney allograft recipients and individuals without indications for surgical procedures. The presence of various pathogenic and opportunistic bacterial strains in oral cavities were revealed by direct microscopic and in vitro culture techniques.
Conclusions:
Colonization of oral cavities of patients requiring surgical treatment by the potentially pathogenic bacteria constitutes the threat of their spread, and development of general infections. Assessment of oral cavity infectious microbiota should be performed as a preventive measure against peri-surgical complications.
This study presents the results of comparative investigations aimed to determine microbiota that can occur in the oral environment in different human populations. The objective of the research was to identify pathogenic oral microbiota, the potential cause of health complications in patients of different population groups.
Material and Methods:
The study included 95 patients requiring dental or surgical treatment; their oral cavity environment microbiota as risk factors of local and general infections were assessed.
Results:
In clinical assessment, differences occurred in oral cavity conditions between patients with malformations of the masticatory system, kidney allograft recipients and individuals without indications for surgical procedures. The presence of various pathogenic and opportunistic bacterial strains in oral cavities were revealed by direct microscopic and in vitro culture techniques.
Conclusions:
Colonization of oral cavities of patients requiring surgical treatment by the potentially pathogenic bacteria constitutes the threat of their spread, and development of general infections. Assessment of oral cavity infectious microbiota should be performed as a preventive measure against peri-surgical complications.
REFERENCES (30)
1.
Marsh PD, Marin MV. Oral microbiology. 4 th ed. Butterworth – Heinemann, London, 1999.
2.
Łuczak M, Swoboda-Kopeć E. Wybrane zagadnienia z mikrobiologii amy ustnej. Czelej, Lublin, 2004 (in Polish).
3.
Marsh PD. Dental plaque: biological significance of a biofilm community lifestyle. J Clin Periodontol. 2005; 32: 7–15.
4.
Murray PR, Baron EJ, Jorgensen JH, Landry ML, Pfaller MA. Manual of clinical microbiology. 9th edition. ASM Press, Washington, USA, 2007.
5.
Chomicz L, Perkowski K, Siemińska-Piekarczyk B, Starościak B, Piekarczyk P, Graczyk Z, et al. Assessment of various components of oral cavity ontocenosis as potential factors for pre and post-surgery complications. II. Opportunistic fungi and protozoans in the oral cavity of orthodontic patients. Chir Czaszk Szczęk Twarz Ortop Szczęk. 2009; 4: 67–76.
6.
Zawadzki PJ, Perkowski K, Starościak B, Dybicz M, Baltaza W, Pionkowski K, et al. Evaluation of selected oral cavity microbiota – risk factors of management complications in patients with masticatory system disorders. Ann Parasitol. 2016; 62(1): 71–76.
7.
Filoche S, Wong L, Sissons CH. Oral biofilms: emerging concepts in microbial ecology. J Dent Res. 2010; 89: 8–18.
8.
Thuy D, Devine D, Marsh P. Oral biofilms: molecular analysis, challenges, and future prospects in dental diagnostics. Clin Cosm Invest Dent. 2013; 5: 11–19.
9.
Marsh PD. The significance of maintaining the stability of the natural microflora of the mouth. Br Dent J. 1991; 171: 174–177.
10.
Wróblewska M, Piotrowska W. Etiologia i epidemiologia zakażeń w praktyce stomatologicznej. In: Łuczak M, Swoboda-Kopeć E, (eds). Wybrane zagadnienia z mikrobiologii jamy ustnej. Wydawnictwo Czelej, Lublin, 2004 (in Polish).
11.
Mahdi SS, Sibilio F, Amenta F. Dental hygiene habits and oral health status of seafarers. Int Marit Health. 2016; 67, 1: 9–13 DOI: 10.5603/IMH.2016.0003.
12.
Perkowski K, Chomicz L, Zawadzki P, Marczyńska-Stolarek M, Padzik M, Piekarczyk P, et al. Assessment of oral cavity microbiota –potential risk factors of local/general opportunistic infections in Polish patients with congenital malformations. FEBS J. 2014; 281(1): 730–731.
13.
Akcam M O, Evirgen S, Uslu O, Memikoglu UT. Dental ano malies in individuals with cleft lip and/or palate. Eur J Orthod. 2010; 32: 207–213.
14.
Michalak E, Łoboda J, Chomyszyn-Gajewska M. Reasons for patients’ visits to dental offices in Cracow in the years 2005–2006 and 2013–2014. Przegl Epidemiol. 2015; 69: 787–794.
15.
Perkowski K, Zawadzki PJ, Starościak B, Dybicz M, Padzik M, Marczyńska-Stolarek M, et al. Składniki mikrobiomu jamy ustnej jako czynniki ryzyka zakażeń lokalnych i uogólnionych u pacjentów bez oraz z wadami wrodzonymi narządu żucia. (with abstract in English) Post Mikrobiol. 2016; 55: 57–67 (in Polish).
16.
Kowalski J. Campylobacter rectus – charakterystyka drobno ustroju oraz jego rola w zapaleniach dziąseł i przyzębia. Dent Med Probl. 2010; 47: 478–481 (in Polish).
17.
Downes J, Mantzourani M, Beighton D, Hooper S, Wilson MJ, Nicholson A, et al. Scardovia wiggsiae sp. nov., isolated from the human oral cavity and clinical material, and emended descriptions of the genus Scardovia and Scardovia inopinata. Int J Syst Evol Microbiol. 2011; 61: 25–29.
18.
Maciejewska M, Bauer M, Dawgul M. Nowoczesne metody zwalczania biofilmu bakteryjnego. Post Mikrobiol. 2016; 55: 3–1 (with abstract in English).
19.
Chomicz L, Piekarczyk J, Fiedor P, Starościak B, Szubińska D, Wojtowicz A. Screening evaluation of oral cavity microorganisms in dialyzed and kidney allograft recipients under chronic immunosuppression. Transplant Proc. 2002; 34(2): 675–676.
20.
Chomicz L, Piekarczyk J, Starościak B, Fiedor P, Piekarczyk B, Szubińska D, Zawadzki P, Walski M. Comparative studies on the occurrence of protozoans, bacteria and fungi in the oral cavity of patients with systemic disorders, Acta Parasitol. 2002; 47: 147–153.
21.
Piekarczyk J, Fiedor P, Chomicz L, Szubińska D, Starościak B, Piekarczyk B, et al. Oral cavity as potential source of infections in recipients with diabetes mellitus. Transplant Proc. 2003; 35(6): 2207–2208.
22.
Perkowski K, Chomicz L, Starościak B, Zadurska M, Szałwiński M, Zawadzki P, et al. Occurrence of pathogenic bacteria in the oral cavity of the orthodontic patients requiring surgical treatment. Stomatol Współcz. 2012; 19: 8–13.
23.
Kurnatowska AJ, Dudko A, Turkowicz M. Familial infections with Trichomonas tenax (O.F. Müller, 1773), Dobel, 1939. Wiad Parazytol. 2004; 50(1): 35–40.
24.
Lunsford RD, Melillo AA, Somerman MJ. Guest editorial for special oral microbes edition. Microbes and Infection 2015; 17: 471–72. www.elsevier.com/locate/micinf.
25.
Belda-Ferre P, Alcaraz LD, Cabrera-Rubio R, Romero H, Simón-Soro A, Pignatelli M, et al. The oral metagenome in health and disease. The ISME J. 2012; 6: 46–56 doi:10.1038/ismej.2011.85.
26.
Bik EM, Long CD, Armitage GC, Loomer P, Emerson J, Mongodin EF, Nelso KE, Gill S R, Fraser-Liggett CM, Relman DA. Bacterial diversity in the oral cavity of 10 healthy individuals. ISME Journal. 2010; 4: 962- 974.
27.
Zaura E, Keijser BJ, Huse SM, Crielaard W. Defining the healthy “core microbiome” of oral microbial communities. BMC Microbiology. 2009; 9: 259. PubMed: 20003481.
28.
Atanasova KR, Yilmaz Ö. Prelude to oral microbes and chronic diseases: past, present and future. Microbes and Infection. 2015; 17: 473–483.
29.
Przybyłowska D, Mierzwińska-Nastalska E, Swoboda-Kopeć E, Rubinsztajn R, Chazan R. Potential respiratory pathogens colonization of the denture plaque of patients with chronic obstructive pulmonary disease. Gerodontology. 2016; 33: 322–327.
30.
Liu Z, Zhang W, Zhang J, Zhou X, Zhang L, Song Y, et al. Oral hygiene, periodontal health and chronic obstructive pulmonary disease exacerbations. J Clin Periodontol. 2012; 39: 45–52.
Improvement of visual identification of the journal - task financed under the agreement No. 618/P-DUN/2019 by the Minister of Science and Higher Education allocated to the activities of disseminating science.
Generation of the DOI (Digital Object Identifier) - task financed under the agreement No. 618/P-DUN/2019 by the Minister of Science and Higher
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.