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Detection of specific IgE as a screening tool for cow and swine breeders' occupational allergic dermatoses.
 
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Department of Occupational Biohazards, Institute of Agricultural Medicine, Lublin, Poland
 
Ann Agric Environ Med. 2000;7(2):145–147
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ABSTRACT:
The study aimed at assessing whether detection of IgE specific to cow and swine allergens can be used as a screening tool for farmers' occupational eczema. Serum samples were taken from 51 farmers. The farmers were questioned about work-related skin symptoms using a nurse-administered questionnaire, verified by a dermatologist. Sera of 29 cow breeders were tested for IgE antibodies specific to cow dander and bovine serum albumin. Sera of 22 swine breeders were tested for IgE specific to swine epithelium, swine serum albumin, and swine urine proteins. Among cow breeders, IgE specific to cow dander was found in one farmer. Among swine breeders, IgE specific to swine epithelium was found also in one subject. On first examination, the cow breeder complained of slight itching of the conjunctivae while working in a cow barn and had no other allergic symptoms. One year later, however, he noticed episodes of hand eczema after contact with cows. In the IgE-positive swine breeder, only mild stationary psoriasis, and no work-related symptoms were found. Among the remaining 28 IgE-negative cow breeders, 11 complained of skin symptoms, but these were not related to working with cows; among 21 IgE-negative swine breeders, 7 subjects had skin diseases, none of which were related to working with swine. We conclude that detection of animal antigen-specific IgE may be an useful screening tool, although an exact assessment of sensitivity and specificity of the method in a larger population of exposed farmers will be required.
 
REFERENCES (18):
1. Epstein S: Milker's eczema. J Allergy 1948, 19, 333–341.
2. Göransson K: Occupational contact urticaria to fresh cow and pig blood in slaughtermen. Contact Dermatitis 1981, 7, 281–282.
3. Iversen M, Dahl R: Specific antigens in dust from swine confinement buildings. Am J Ind Med 1994, 25, 49–51.
4. Iversen M, Pedersen B: The prevalence of allergy in Danish farmers. Allergy 1990, 45, 347–353.
5. Kalveram KJ, Kastner H, Forck G: Nachweis von spezifischen IgE-Antikörpern bei Tierärzten mit Kontakturtikaria. Z Hautkr 1986, 61, 75–81.
6. Kanerva L, Susitatival P: Cow hair: the most common cause of occupational contact urticaria in Finland. Contact Dermatitis 1996, 35, 309–310.
7. Kroidl RF, Schwichtenberg U: Allergien vom Typ I in der Landwirtschaft. Allergologie 1999, 22, 230-236.
8. Mahler V, Diepgen TL, Heese A, Peters KP: Protein contact dermatitis due to cow dander. Contact Dermatitis 1998, 38, 47–48.
9. Malanin G, Kalimo K: Occupational contact dermatitis due to delayed allergy to pig epithelia. Contact Dermatitis 1992, 26, 134–135.
10. Matson SC, Swanson MC, Reed CE, Yunginger JW: IgE and IgG-immune mechanisms do not mediate occupation-related respiratory or systemic symptoms in hog farmers. J Allergy Clin Immunol 1983, 72, 299–304.
11. Prahl P, Roed–Petersen J: Type I allergy from cows in veterinary surgeons. Contact Dermatitis 1979, 5, 33–38.
12. Rautalahti M, Terho EO, Vohlonen I, Husman K: Atopic sensitization of dairy farmers to work-related and common allergens. Eur J Respir Dis 1987, 152(Suppl), 155–164.
13. Roth WG. Ekzem und Asthma durch Rinder- und Pferdehaare. Berufsdermatosen 1968, 16, 278–282.
14. Schneider W, Coppenrath R, Ruther H: Über Tierhaar–Allergie. Berufsdermatosen 1960, 8, 1–13.
15. Spiewak R: Occupational dermatoses in farmers – a proposal for a diagnostic procedure. Ann Agric Environ Med 1999, 6, 63–72.
16. Susitaival P, Husman L, Hollmen A, Horsmanheimo M, Husman K, Hannuksela M: Hand eczema in Finnish farmers. A questionnaire– based clinical study. Contact Dermatitis 1995, 32, 150–155.
17. Timmer C, Coenraads PJ: Allergic contact dermatitis from cow hair and dander. Contact Dermatitis 1996, 34, 292–293.
18. Van Ketel WG, van Diggelen MW: A farmer with allergy to cows. Contact Dermatitis 1982, 8, 279.
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