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RESEARCH PAPER
 
 

Selected parameters of immunological response in hop growers during the periodof intensive application of pesticides.

 
1
Departament of Pathomorphology, Institute of Agricultural Medicine, 20-950 Lublin,PO Box 185, Poland.
Ann Agric Environ Med 2004;11(2):227–231
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ABSTRACT:
The aim of the study was determination of selected parameters of immunologicalresponse among hop growers and farmers in conditions of intensive exposure to means of plant protection.Survey data was collected from 238 males aged 25-70 living in the area of Wilków near Puławy (LublinRegion). Control group were males from the area of Witoszyn (Lublin Region)--53 people aged 25-70 occupiedmainly with land cultivation. Based on an environmental survey conducted among hop growers and farmers,the respondents were divided into 3 age groups: 25-40, 41-55 and 56-70. Laboratory tests covered thedetermination of selected morphological parameters, phagocytic test, NBT test, and myeloperoxidasis (MPO)concentration in blood serum of hop growers and farmers.A significant decrease was noted in the numberof platelets in the general population of hop growers and in individual age groups, compared to the controlgroups of farmers. Analysis of individual sub-populations of leukocytes showed a significantly highernumber statistically of basophils and lymphocytes among hop growers, compared to farmers. A detailedanalysis of the degree of phagocytic and bactericidal activity of neutrophils allowed us to presume thatduring the period of spraying there occurred a mobilisation of the granulocytic system, manifested bythe presence of over 90% of neutrophils of intensified phagocytic activity, and 20% of neutrophils ofintensified bactericidal activity. The preparations prepared by the routine NBT test method were analysedwith the use of LUCIA computer programme (version 4.51). The analysis of the level of MPO in blood serumin the populations examined showed the presence of statistically significant differences. In hop growers,the MPO level was significantly higher statistically (60.0 ng/ml), compared to the control group of farmers(43.4 ng/ml).
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eISSN:1898-2263
ISSN:1232-1966