Oxidative stress and total antioxidant status in term newborns and their mothers
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Department of Neonatology, Medical Centre of Postgraduate Education, Warsaw, Poland
Department of Neonatology and Neonatal Intensive Care, Medical University, Warsaw, Poland
Department of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, Warsaw, Poland
I Department of Obstetrics and Gynecology, Medical Centre of Postgraduate Education, Warsaw, Poland
Maria Wilinska   

Department of Neonatology, Medical Centre of Postgraduate Education, Warsaw, Poland
Ann Agric Environ Med. 2015;22(4):736–740
The peripartum period and delivery are considered critical for maintaining a balance between the production of free oxygen radicals and functional incompetence of the antioxidant system of a foetus and a neonate.

The aim of the study was to evaluate the oxidoreductive state of mothers and their newborns immediately after delivery and in the first few days after birth.

Material and Methods:
Eighty-five mothers and their healthy, term newborns were included into the prospective study. Total antioxidant capacity (TAC) and thiobarbituric acid reactive substances (TBARS) in maternal placenta and milk, as well as blood and urine of the neonates on the first and third day after birth, were examined.

Elevated levels of TBARS were found in maternal placenta and neonatal blood on the third day after birth, but low concentrations were observed in maternal milk. On the contrary, total antioxidant status (TAS) showed a declining tendency in neonatal blood and an increasing tendency in breast milk. Markers of oxidative stress and antioxidant capacity were independent of the mode of delivery.

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