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RESEARCH PAPER
 
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One-step synthesis of highly-biocompatible spherical gold nanoparticles using Artocarpus heterophyllus Lam. (jackfruit) fruit extract and its effect on pathogens

 
1
Department of Biotechnology, Shridevi Institute of Engineering & Technology, Tumkur, Karnataka, India
2
Department of Chemistry and Technology of Polymers, Cracow University of Technology, Cracow, Poland
3
Institute of Inorganic Chemistry and Technology, Cracow University of Technology, Cracow, Poland
Ann Agric Environ Med 2015;22(1):84–89
KEYWORDS:
ABSTRACT:
Introduction:
Novel approaches for the synthesis of gold nanoparticles (AuNPs) are of great importance due to its vast spectrum of applications in diverse fields, including medical diagnostics and therapeutics. Te presented study reports the successful AuNPs’ synthesis using Artocarpus heterophyllus Lam. extract, and provides detailed characterization and evaluation of its antibacterial potential. [b]Objective[/b]. The aim was to develop a cost-effective and environmentally friendly synthesis method of gold nanoparticles using aqueous fruit extract of Artocarpus heterophyllus Lam. as a reducing and capping agent, which has proven activity against human pathogens, such as microbial species [i]E.coli[/i] and Streptobacillu sps.

Material and Methods:
Characterizations were carried out using ultraviolet-visible (UV-Vis) spectrophotometry, scanning electron microscopy (SEM), energy dispersive X-ray and Fourier-Transform infra-red spectroscopy (FT-IR).

Results:
SEM images showed the formation of gold nanoparticles with an average size of 20–25 nm. Spectra collected while infra-red analysis contained broad peaks in ranges from 4000–400 cm -1 .

Conclusions:
It can be concluded that the fruit of Artocarpus heterophyllus Lam. can be good source for synthesis of gold nanoparticles which showed antimicrobial activity against investigated microbes, in particul E. coli, and Streptobacillus. An important outcome of this study will be the development of value-added products from the medicinal plant Artocarpus heterophyllus Lam. for the biomedical and nanotechnology-based industries.



CORRESPONDING AUTHOR:
Agnieszka Sobczak-Kupiec   
Institute of Inorganic Chemistry and Technology, Cracow University of Technology, Cracow, Poland
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eISSN:1898-2263
ISSN:1232-1966