Effect of selected socio-demographic, clinical and biochemical factors on self-reported quality of life among post-menopausal women with osteoporosis
More details
Hide details
Department of Nursing, Faculty of Health Sciences, Poznan University of Medical Sciences, Poland
Department of Mother and Child Health, Faculty of Health Sciences, Poznan University of Medical Sciences, Poland
Ann Agric Environ Med. 2013;20(4):843–848
Introduction: The goal of health care with relation to women with osteoporosis is the prevention of fractures, maintenance of independence, and good quality of life. Objective: To discover how selected socio-demographic, clinical and biochemical factors affect positively or negatively the overall assessment of the quality of life, and to assess the quality of life in specific domains among women with osteoporosis. Materials and methods: The study group covered 85 women with osteoporosis. Self-reported quality of life was evaluated using WHOQOL-100. In order to determine factors affecting the self-reported of quality of life the logistic regression analysis was applied. Results: The physical domain was associated with decreased height (OR=2.13; 95%CI 1.04–4.35), anxiety (OR=1.30; 95%CI 1.14–1.49) and depression (OR=1.32; 95%CI 1.09–1.59). The psychological domain was associated with previous fractures (OR=4.76; 95%CI 2.22–11.11), deformities of the back (OR=2.13; 95%CI 1.08–4.17) and anxiety (OR=1.16; 95%CI 1.02–1.16). The level of independence and of social domain were associated with performance of occupational activity, respectively (OR=0.93; 95%CI 0.88–0.97) (OR=0.96; 95%CI 0.88–0.98). The social domain was associated with decreased height (OR=2.38; 95%CI 1.12–5.26), deformities of the back (OR=1.28; 95%CI 1.02–4.35), BMI (OR=1.14; 95%CI 1.05–1.23), anxiety (OR=1.41; 95%CI1.20–1.64) and depression (OR=1.23; 95%CI 1.03–1.49). Conclusion: The factors determining poor quality of life were decreased height, deformity of the back, previous fractures, elevated FSH level, anxiety and depression. The factors determining a good self-reported quality of life were higher level of education and occupational activity.
Raspe H. Quality of life measurement in rheumatology. In: Quality of life and health. Concepts, Methods and Applications. Blackwell WissVerl, Vienna, 1995: 95–.
Schoor NM, Smit JH, Twisk JW, Lips P. Impact of vertebral deformities, osteoarthritis, and other chronic diseases on quality of life: a population – based study. Osteoporos Int. 2005;16: 749–756.
Pluijm SMF, Tromp AM, Smit JH, Deeg DJH, Lips P. Consequences of vertebral deformities in older men and women. J Bone Miner Res. 2000; 15: 1564–1572.
Silverman SL, Shen W, Minshall ME, Xie S, Moses KH. Prevalence of depressive symptoms in postmenopausal women with low bone mineral density and/or prevalent vertebral fracture: results from the Multiple Outcomes of Raloxifene Evaluation (MORE) study. J Rheumatol. 2007; 34: 140–144.
Bączyk G, Opala T, Kleka P. Depresja i jakość życia kobiet z osteoporozą pomenopauzalną. Ortop Traum Rehab. 2009; 11 supl, (2): 125–126.
Stadnicka G, Iwanowicz-Palus G, Mazurek A, Pięta B. The feeling of life satisfaction in patients after hysterectomy. Ginekol Pol. 2012; 83(5): 347–352 (in Polish).
Rechberger T, Miotła P, Skorupski P, et al. The quality of life of patients with overactive bladder after local injections of botulinum toxin A – a preliminary report. Ginekol Pol. 2010; 81(1): 24–30 (in Polish).
Post M W M. Quality of life and The ICIDH: towards an integrated conceptual model for rehabilitation outcome research. Clin Rehabil. 1999; 13: 5–15.
WHOQOL Group. The World Health Organization Quality of Life Assessment (WHOQOL). Position paper from the World Health Organization. Soc Sci Med. 1995; 41: 1403–1409.
Jaracz K, Wołowicka L, Kalfos M. Analiza walidacyjna polskiej wersji WHOQOL-100. In: Wołowicka L. Jakość życia w naukach medycznych. Wydawnictwo Akademii Medycznej, Poznań 2001: 291–302.
Zawisza K, Tobiasz-Adamczyk B, Nowak W. et al. Validity and reliability of the quality of life questionnaire (EORTC QLQ C30) and its Brest cancer module (EORTC QLQ BR23). Ginekol Pol. 2010;.
Nowakowska-Głąb A, Maniecka-Bryła I, Wilczyński J, Nowakowska D. Evaluation of antenatal quality of life of hospitalized women with the use of Mother-Generated Index – pilot study. Ginekol Pol. 2012; 81(7): 521–527 (in Polish).
Bączyk G, Opala T, Kleka P. Quality of life in postmenopausal women with reduced bone mineral density: psychometric evaluation of the Polish version of QUALEFFO- 41. Arch Med Sci. 2011; 7(3): 476–485.
World Health Organization Study Group. Assessment of fracture risk and its application to screening for post-menopausal osteoporosis. In WHO Technical Report Series, 1994, No, 843 WHO, Geneva.
Satoh K, Kasama F, Itoi E, Tanuma S, Wakamatsu E. Clinical features of spinal osteoporosis: spinal deformity and pertinent back pain. Contemp Orthop. 1988; 16: 23–30.
Majkowicz M. Praktyczna ocena efektywności opieki paliatywnej – wybrane techniki badawcze. In: de Walden-Gałuszko K, Majkowicz M. Ocena jakości opieki paliatywnej w teorii i praktyce. Akademia Medyczna Gdańsk, Zakład Medycyny Paliatywnej, Gdańsk, 2000.
Lips P, van Schoor N M. Quality of life in patients with osteoporosis. Osteoporos Int. 2005; 16: 447–455.
Oleksik AM, Ewing S, Shen W, van Schoor NM, Lips P. Impact of incident vertebral fractures on health related quality of life (HRQOL) in postmenopausal women with prevalent vertebral fractures. Osteoporos Int. 2004; 19: 861–870.
Oleksik A M, Lips P, Dawson A. Health-Related Quality of Life (HRQOL) in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res. 2000; 15: 1384–1392.
Miyakoshi N, Itoi E, Kobayashi M, Kodama H. Impact of postural deformities and spinal mobility on quality of life in postmenopausal osteoporosis. Osteoporos Int. 2003; 14: 1007–1012.
Jahelk B, Dorner T,Terkula R, et al. Health-related quality of life in patients with osteopenia or osteoporosis with and without fractures in a geriatric rehabilitation department. Wien Med Wochenschr, 2009; 159: 235–240.
Abourazzak FE, Allali F, Rostom S, et al. Factors influencing quality of life in Moroccan postmenopausal women with osteoporotic vertebral fracture by ECOS 16 questionnaire. Health Qual. Life Outcomes 2009; 7:23 doi: 10.1186/1477–7525–7–23.
Fechtenbaum J, Cropet C, Kolta S, et al. The severity of vertebral fractures and health-related quality of life in osteoporotic postmenopausal women. Osteoporos Int. 2005; 16: 2175–2179.
Bianchi ML, Orsini MR, Saraifoger S, et al. Quality of life in postmenopausal osteoporosis. Health Qual Life Outcomes 2005; 3: 78–84.
Krajewska-Kułak E. Chilicka M. Kułak W, et al. Assessment of physician- patient trust in the obstetrics and gynecology department in Poland and Greece. Ginekol Pol. 2011; 82(12): 905–910 (in Polish).
Szkutnik-Fiedler D, Jędrzejczak M, Grześkowiak E, et al. The role of phytoestrogen therapy in relieving postmenopausal symptoms. Ginekol Pol. 2010; 81(12): 929–934 (in Polish).
Dallanezi G, Nahas EAP, Freire BF, et al. Quality of life of women with low bone mass in postmenopause. Rev Bras Ginecol Obstet, 2011; 33: 133–138.
Milewicz T, Krzysiek J, Rogatko I, et al. The somatotropic axis in postmenopausal women Turing six month of transdermal continuous 17β-estradiol administration combined with oral medroxyprogesterone. Ginekol Pol. 2011; 82(4): 254–258 (in Polish).
Ferreira NO, Arthuso M, Silva R, et al. Quality of life in women with postmenopausal osteoporosis: Correlation between QUALEFFO 41 and SF-36. Maturitas 2009; 62: 85–90.
Szpak R, Folwarczny W, Drozdzol A, et al. Partner relationships In menopausal period. Ginekol Pol. 2010; 81(2): 115–119 (in Polish).
Perżyło K, Kulik – Rechberger B, Gałczyński K, Rechberger T. Intracrinology and dehydroepiandrosterone – a new perspective for the use of androgens In hormone replacement therapy In postmenopausal women. Ginekol Pol. 2011; 82(9): 690–695 (in Polish).
Sezer N, Tomruk-Sutbeyaz S, Kibar S, Koseoglu F, Aras M. Determinants of quality of life in postmenopausal osteoporosis. F T R Bil Der J P M R Sci. 2009; 12: 19–25.
Tashiro A, Kakuta H, Tanaka N, Takeuchi Y. Relationship between health-related quality of life domains and bone status in postmenopausal Japanese women. Menopause 2006; 13: 846–849.
Kessenich CR, Guyatt GH, Rosen CJ. Health-related quality of life and participation in osteoporosis clinical trials. Calcified Tissue Int. 1998; 62: 189–192.