0.829
IF
20
MNiSW
166.26
ICV
Online first
RESEARCH PAPER
 
CC BY-NC-ND 3.0
 
 

Decreased NK cell activity after partial vulvectomy in pregnant patient with vulvar intraepithelial neoplasia 3 (VIN3)

Monika Ohams 2,  
 
1
Department of Gynecology and Gynecological Oncology, Military Institute of Medicine, Warsaw, Poland
2
Department of Clinical Immunology, Transplantation Institute, University Medical School, Warsaw, Poland
KEYWORDS:
ABSTRACT:
[b] Abstract Introduction and objective[/b]. The study presents the problem of immune disturbances in pregnant women with vulvar carcinoma in situ (VIN3). [b]Material and methods[/b]. NK cell and T reg activity in the study patient were analysed using flow cytometry. [b]Results[/b]. Decreased NK cell activity and but increased T reg activity were observed after vulvectomy, with subsequent successful pregnancy outcome. Conclusions. Although vulvar cancer may influence immune cell activity, this issue merits further study
eISSN:1898-2263
ISSN:1232-1966