ORIGINAL ARTICLES

AAEM

Ann Agric Environ Med 2002, 9, 29-31

THE USE OF THE RADIOISOTOPE METHOD IN STUDIES OF PESTICIDE
PENETRATION INTO THE EYEBALL

Marek Gerkowicz1, Ewa Wrˇblewska1, Waldemar Turski2

1II Department of Ophthalmology, Medical Academy, Lublin, Poland
2Department of Toxicology, Institute of Agricultural Medicine, Lublin, Poland

Full text available in Adobe Acrobat format.Full text available in Adobe Acrobat Format

Gerkowicz M, Wrˇblewska E, Turski W: The use of the radioisotope method in studies of pesticide penetration into the eyeball. Ann Agric Environ Med 2002, 9, 29-31.

Abstract: The studies concerning the effects of pesticides on the human body focused mainly on their local action or chronic poisoning of the organism. In this study we examine the pesticide penetration into the eyeball resulting from direct contact with the eye. We used an isotope-labelled carbamate pesticide - carbaryl. The determinations of the amount and concentration of this substance in the cornea, aqueous humour, vitreous humour and retina were performed using the method measuring ▀ radiation emitted by radioactive carbon. The results revealed measurable concentrations of labelled carbamate in the cornea and aqueous humour 10 and 30 min after application. The levels of this pesticide in the vitreous humour and retina were very low and difficult to analyse statistically. The described method appears to be useful in determining the range and rate of eye penetration by environmental toxins having direct contact with the eyeball

Address for correspondence: Marek Gerkowicz, Czarkowskiego 17A, 20-735 Lublin

Key words: eye, carbaryl, pesticides, ▀ radiation


Back to the Table of Contents