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Ann Agric Environ Med 2000, 7, 141-143

LYME BORRELIOSIS AND MULTIPLE SCLEROSIS: ANY CONNECTION?
A SEROEPIDEMIC STUDY

Jolanta Chmielewska-Badora, Ewa Cisak, Jacek Dutkiewicz

Department of Occupational Biohazards, Institute of Agricultural Medicine, Lublin, Poland

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Chmielewska-Badora J, Cisak E, Dutkiewicz J: Lyme borreliosis and multiple sclerosis: any connection? A seroepidemic study . Ann Agric Environ Med 2000, 7, 141-143.

Abstract: A total of 769 adult neurological patients hospitalised in clinics and hospitals situated in the Lublin region (eastern Poland) were examined during the years 1997-2000 with ELISA test for the presence of anti-Borrelia burgdorferi sensu lato antibodies. A statististically significant (p = 0.0422) relationship was found between the clinically confirmed diagnosis of multiple sclerosis and the positive serologic reaction with Borrelia antigen. Ten out 26 patients with multiple sclerosis (38.5%) showed positive serologic reaction to Borrelia, whereas among the total number of examined neurological patients the frequency of positive findings was twice as low (19.4%). The result suggests that multiple sclerosis may be often associated with Borrelia infection.

Address for correspondence: Jolanta Chmielewska-Badora, MS, Department of Occupational Biohazards, Institute of Agricultural Medicine, Jaczewskiego 2, 20-090 Lublin, Poland.

Key words: Lyme borreliosis, multiple sclerosis, seroepidemiology, ELISA.


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