Detecting DNAs of Anaplasma phagocytophilum and Babesia in the blood of patientssuspected of Lyme disease.
More details
Hide details
Department of Infectious Diseases and Neuroinfections, Medical University ofBialystok, Poland.
Ann Agric Environ Med 2004;11(2):351–354
Co-occurrence of granulocytic anaplasmosis, borreliosis and babesiosisin humans is a result of common vectors for the respective pathogens of these diseases, most commonlyticks from the genus Ixodes. Studies on ticks in Europe and also in Poland have shown that several pathogensmay co-occur in individuals of I. ricnus. A total of 96 hospitalised patients infected or suspected ofbeing infected with borreliosis were screened for A. phagocytophilum and Babesia sp. DNA. Positive resultsof PCRs for A. phagocytophilum DNA were obtained for 10 patients, 8 of whom were diagnosed with borreliosisearlier, and 4 of whom were diagnosed with tick-borne encephalitis (on the basis of serological studiesof serum and cerebrospinal fluid). None of the 10 patients had clinical or biochemical markers of anaplasmosis,corroborating the existence of asymptomatic anaplasmosis or self-limiting course. in Europe. Similarly,Babesia DNA was not found in the blood of any of the patients. The results of the studies show that indiagnosing tick-borne diseases, clinical examinations should consider infection by two or even threetick-borne pathogens.