Decreased NK cell activity after partial vulvectomy in pregnant patient with vulvar intraepithelial neoplasia 3 (VIN3)
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Department of Gynecology and Gynecological Oncology, Military Institute of Medicine, Warsaw, Poland
Department of Clinical Immunology, Transplantation Institute, University Medical School, Warsaw, Poland
Ann Agric Environ Med 2017;24(3):459–463
Introduction and objective:
The study presents the problem of immune disturbances in pregnant women with vulvar carcinoma in situ (VIN3).

Material and Methods:
NK cell and T reg activity in the study patient were analysed using flow cytometry.

Decreased NK cell activity and but increased T reg activity were observed after vulvectomy, with subsequent successful pregnancy outcome.

Although vulvar cancer may influence immune cell activity, this issue merits further study.

Malgorzata Jerzak   
Department of Gynecology and Gynecological Oncology, Military Institute of Medicine, Warsaw, Poland
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